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US 2019/0194281 A1Published application
Delivery of an agent to autophagic and apoptotic cells by vesicles with a protein expressed on surface thereof
AssigneeTzu Chi University
InventorsHsin-Hou CHANG, Der-Shan SUN
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Abstract
The invention creates engineered surface protein expression on vesicles for specific targeting and delivery of agents to autophagic and apoptotic cells. Moreover, the vesicles of the invention can achieve a synergistic effect on the targeting and drug delivery to autophagic and apoptotic cells and autophagic and apoptotic cells-containing tissues.
Claims21
A protein-conjugated vesicle, comprising one or more lectins or a fragment thereof expressed or conjugated to the surface of the vesicle and optionally an agent.
Dependencies are inferred from the claim text.