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US 2019/0194218 A1Published application
Crystalline forms of therapeutic compounds and uses thereof
AssigneeKala Pharmaceuticals, Inc.
InventorsMinh Ngoc Nguyen, Winston Zapanta Ong
Life of this patent
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Abstract
Described herein are crystalline forms of Compound 1 useful for the prevention and treatment of angiogenic ocular conditions; methods of treating a disease comprising; processes for preparing; and kits comprising, the same.
Claims15
A method of treating a disease comprising administering to a subject in need thereof a therapeutically effective amount of a crystalline form of Compound 1:
- wherein the crystalline form has an X-ray powder diffraction (XRPD) pattern comprising peaks at 7-8 degrees 2θ, 12.5-13.5 degrees 2θ, 14.5-15.5 degrees 2θ, 17-18 degrees 2θ, and 26-27 degrees 2θ, or
- a pharmaceutical composition comprising the crystalline form.
A method of inhibiting aberrant signaling of a growth factor comprising administering to a subject a therapeutically effective amount of a crystalline form of Compound 1:
- wherein the crystalline form has an XRPD pattern comprising peaks at 7-8 degrees 2θ, 12.5-13.5 degrees 2θ, 14.5-15.5 degrees 2θ, 17-18 degrees 2θ, and 26-27 degrees 2θ, or a pharmaceutical composition comprising the crystalline form.
A kit comprising a crystalline form of Compound 1:
- wherein the crystalline form has an X-ray powder diffraction (XRPD) pattern comprising peaks at 7-8 degrees 2θ, 12.5-13.5 degrees 2θ, 14.5-15.5 degrees 2θ, 17-18 degrees 2θ, and 26-27 degrees 2θ, or
- a pharmaceutical composition comprising the crystalline form.
Dependencies are inferred from the claim text.