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US 2019/0176152 A1Published application
Microfluidic Surface-Mediated Emulsion Stability Control
Assignee10x Genomics, Inc.
InventorsRajiv Bharadwaj, Tobias Daniel Wheeler, Kevin Ness, Benjamin Hindson
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Abstract
A microfluidic emulsion droplet generation system and methods of use thereof are provided. The system may include a microfluidic substrate having a flow path configured and arranged for emulsion droplet generation, at least one textured surface in the flow path configured and arranged for inducing surface-mediated coalescence of emulsion droplets; and at least one channel junction in the flow path for emulsion droplet formation.
Claims49
A microfluidic emulsion droplet generation system comprising:
- a) a microfluidic substrate having a flow path configured and arranged for emulsion droplet generation;
- b) at least one textured surface in the flow path configured and arranged for inducing surface-mediated coalescence of emulsion droplets;
- and
- c) at least one channel junction in the flow path for emulsion droplet formation,
- wherein the at least one textured surface is disposed in the flow path downstream of the channel junction.
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Dependencies are inferred from the claim text.