Magnesium-containing oxytocin formulations and methods of use
AssigneeTrigemina, Inc.
InventorsDean CARSON, David C. YEOMANS
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Abstract
Disclosed are methods and compositions for the treatment of autism spectrum disorder, related disorders and symptoms of such disorders, comprising co-administration of an oxytocin peptide and magnesium ions. Co-administration of an oxytocin peptide and magnesium ions results in a synergistic or enhanced effect on reducing social and communication deficits in a patient suffering from an autism spectrum disorder.
Claims46
A method for treating an autism spectrum disorder, a disorder manifesting one or more symptoms associated with an autism spectrum disorder, social and communication deficits, or an anxiety, comprising administering to a subject in need thereof an effective dose of an oxytocin peptide and magnesium ions, wherein co-administration of the oxytocin peptide and the magnesium ions produces a synergistic or enhanced effect.
A method for treating an autism spectrum disorder, a disorder manifesting one or more symptoms associated with an autism spectrum disorder, social and communication deficits, or an anxiety, comprising administering to a subject in need thereof an effective dose of an oxytocin peptide and magnesium ions, wherein the effective dose of the oxytocin peptide and the magnesium ions is administered intranasally in a liquid formulation, and the volume of the liquid formulation administered is between about 5 μL and about 1000 μL.
A composition comprising an oxytocin peptide and magnesium ions, wherein the oxytocin peptide and the magnesium ions are in an amount that produces a synergistic or enhanced effect when used in the treatment of anxiety.
Dependencies are inferred from the claim text.