# US 2019/0172270 A1 · A Method and Apparatus for Transforming Physical Measurement Data of a Biological Organ > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2019/0172270 A1 - Document ID: US20190172270A1 - Status: Published application - Kind: A1 - Application number: 16/323,608 - Filed: 2017-08-10 - Published: 2019-06-06 - Earliest claimed: 2016-08-10 - Assignees: UCL Business PLC - Applicants: UCL Business PLC - Inventors: Carole Sudre; M Jorge Cardoso; Sebastien Ourselin; Jonathan Rohrer - Web page: https://patentgrep.com/patent/US20190172270A1 ## CPC - G06T 19/20: Editing of three-dimensional [3D] images, e.g. changing shapes or colours, aligning objects or positioning parts - G06T 15/08: Volume rendering - G06T 17/10: Constructive solid geometry [CSG] using solid primitives, e.g. cylinders, cubes - G16H 30/40: for processing medical images, e.g. editing - G16H 50/50: for simulation or modelling of medical disorders - G06T 2210/41: Medical - G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA ## Abstract An apparatus is configured for performing a computer-implemented method comprising: receiving data comprising physical measurements of a biological organ across a three-dimensional (3D) volume, the organ having a hierarchical structure of elements with multiple levels; transforming the physical measurement data into a two-dimensional (2D) data representation having first and second axes, wherein the first axis corresponds to location of an element a spatial path through the three-dimensional volume based on the hierarchical structure of the organ, and the second axis corresponds to descending successive levels through said hierarchical structure; and outputting the two-dimensional data representation to an apparatus for display. ## Claims ### Claim 1 A computer-implemented method comprising: receiving data comprising physical measurements of a biological organ across a three-dimensional (3D) volume, the organ having a hierarchical structure of elements with multiple levels; transforming the physical measurement data into a two-dimensional (2D) data representation having first and second axes, wherein the first axis corresponds to location of an element along a spatial path through the three-dimensional volume based on the hierarchical structure of the organ, and the second axis corresponds to descending successive levels through said hierarchical structure; and outputting the two-dimensional data representation to an apparatus for display. ### Claim 2 (depends on 1) The method of claim 1, wherein transforming includes: providing the spatial path through the three-dimensional volume, the spatial path for a given level of a hierarchical structure passing through elements within the given level of the hierarchical structure to define an ordering for the elements within the given level, said ordering reflecting at least in part the relative positions of the elements in the three-dimensional volume. ### Claim 3 (depends on 2) The method of claim 2, wherein the same spatial path is used for each level of the hierarchical structure. ### Claim 4 The method of any preceding claim, wherein the spatial path has a first portion through a first region of the organ, and a second portion through a second region of the organ, wherein the first and second portions of the spatial path are symmetric. ### Claim 5 The method of any preceding claim, further comprising: identifying a sub-volume of the three-dimensional (3D) volume corresponding to a given element in the hierarchical structure of the biological organ; and mapping the physical measurement data within the sub-volume to a corresponding location in the 2D representation according to (i) the level in which the given element is located in the hierarchical structure, and (ii) the location of the given element along said spatial path. ### Claim 6 The method of any preceding claim wherein the identifying and mapping is performed for each element in the hierarchical structure. ### Claim 7 The method of any preceding claim, wherein the first axis is scaled in accordance with the hierarchical structure, such that a given branch of the hierarchical structure has a consistent size across all levels. ### Claim 8 (depends on 7) The method of claim 7, wherein all elements within a given branch and at a given level of the hierarchical structure have the same size. ### Claim 9 (depends on 7) The method of claim 7, wherein all elements correspond to a respective sub-volume of the three-dimensional (3D) volume, and all elements within a given branch and at a given level of the hierarchical structure are scaled in the 2D representation relative to one another according to the physical size of their respective sub-volumes. ### Claim 10 (depends on 7) The method of claim 7, wherein the size of an element in a given hierarchical level is scaled in the 2D representation in accordance with the number of elements subordinate to the element in the given hierarchical level. ### Claim 11 The method of any of the preceding claims, wherein the two-dimensional representation is based on a polar coordinate system, wherein the first axis corresponds to the angular coordinate and the second axis corresponds to the radial coordinate. ### Claim 12 (depends on 11) The method of claim 11, wherein the hierarchy is represented by a series of concentric rings, and the uppermost hierarchical level is represented by the innermost ring. ### Claim 13 (depends on 11) The method of claim 11, wherein the two-dimension representation comprises at least an upper level and a lower level of the hierarchical structure, wherein the lower level is based on an angular coordinate corresponding to the first axis, and the upper level is located radially outside the lower level, and is based on a homotopic mapping of said angular coordinate. ### Claim 14 (depends on 13) The method of claim 13, wherein the upper level is configured as a pair of linear arrangements located on opposing sides of the lower level. ### Claim 15 (depends on 1, 2, 3, 4, 5, 6, 7, 8, 9, 10) The method of any of claims 1 to 10, wherein the two-dimensional representation is based on Cartesian (x-y) coordinates, wherein the first axis of the 2D representation corresponds to one of the x or y axis and the second axis of the 2D representation corresponds to the other of the x or y axis. ### Claim 16 The method of any the preceding claim, wherein all elements correspond to a respective sub-volume of the three-dimensional (3D) volume, and the method further comprising averaging the physical measurement data for an element over the respective sub-volume for that element. ### Claim 17 The method of any preceding claim, wherein the physical measurement data corresponding to a particular element of the hierarchical structure is represented by a colour according to the value of the physical measurement data for that element. ### Claim 18 The method of any preceding claim, wherein the physical measurement data corresponding to a particular element of the hierarchical structure is represented by a sizing of a display element along the second axis, within one level of the hierarchy. ### Claim 19 The method of any preceding claim, wherein the 2D representation preserves a symmetry of the biological organ. ### Claim 20 The method of any preceding claim, wherein the biological organ is the brain. ### Claim 21 The method of any preceding claim, wherein the physical measurement data comprises data acquired from an imaging system or other measurement system, or is derived from such data. ### Claim 22 The method of any of the preceding claims, further comprising: displaying the two-dimensional representation at the apparatus for display; receiving an input in association with the displayed two-dimensional representation; and modifying the two-dimensional representation in accordance with the received input. ### Claim 23 A computer readable media comprising instructions that, when executed on a computer, perform the method of any preceding claim. ### Claim 24 Apparatus configured to perform the operations of: receiving data comprising physical measurements of a biological organ across a three-dimensional (3D) volume, the organ having a hierarchical structure of elements with multiple levels; transforming the physical measurement data into a two-dimensional (2D) data representation having first and second axes, wherein the first axis corresponds to location of an element along a spatial path through the three-dimensional volume based on the hierarchical structure of the organ, and the second axis corresponds to descending successive levels through said hierarchical structure; and outputting the two-dimensional data representation to an apparatus for display. ### Claim 25 (depends on 24) The apparatus of claim 24, wherein said apparatus comprises one or more processors and computer program instructions for execution by the one or more processors to perform said operations. ### Claim 26 (depends on 24, 25) The apparatus of claim 24 or 25, further comprising a display apparatus for displaying the output two-dimensional representation. ### Claim 27 (depends on 24, 25, 26) The apparatus of any of claims 24 to 26, wherein the apparatus is integrated into an image or physical measurement acquisition system. ### Claim 28 A method or apparatus substantially as hereinbefore described with reference to the accompanying drawings.