# US 2019/0168208 A1 · Apparatus for Detecting the Presence or Absence of An Analyte in Samples

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- Number: US 2019/0168208 A1
- Document ID: US20190168208A1
- Status: Published application
- Kind: A1
- Application number: 16/209,293
- Filed: 2018-12-04
- Published: 2019-06-06
- Earliest claimed: 2017-12-06
- Assignees: Hangzhou Biotest Biotech Co., LTD.
- Applicants: Hangzhou Biotest Biotech Co., LTD.
- Inventors: Kefeng Zhang
- Web page: https://patentgrep.com/patent/US20190168208A1

## CPC

- B01L 3/502: {with fluid transport, e.g. in multi-compartment structures}
- G01N 33/54388: {based on lateral flow}
- B01L 2200/0621: Control of the sequence of chambers filled or emptied
- B01L 2200/143: Quality control, feedback systems
- B01L 2300/0825: Test strips
- B01L 2300/0832: cylindrical, tube shaped
- B01L 2300/0858: Side walls
- B01L 2300/123: Flexible; Elastomeric
- B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)

## Abstract

The present invention provides an apparatus for detecting the presence or absence of an analyte in samples, comprising: a collection chamber for receiving liquid sample, comprising an opening; a testing element for testing the analyte in liquid sample; and a cover body for covering the opening of the collection chamber; wherein the apparatus further comprises a prompting device for prompting if the cover body is covered to a specified location, the prompting device gives prompt by making a sound, wherein the prompting device comprises a non-elastic element and an elastic element, the non-elastic element is located on the collection chamber, the elastic element is located on the cover body, the elastic element is a part of the cover body. It is easy to perform detection using this apparatus, with low processing cost.

## Claims

### Claim 1

An apparatus for detecting analyte in a sample, comprising a collection chamber for receiving liquid sample, comprising an opening; a testing element for testing the analyte in liquid sample; and a cover body for covering the opening of the collection chamber; wherein the apparatus further comprises a prompting device for prompting if the cover body is covered to a specified location, the prompting device gives prompt by making a sound, wherein the prompting device comprises a non-elastic element and an elastic element, the non-elastic element is located on the collection chamber, the elastic element is located on the cover body, the elastic element is a part of the cover body, wherein the elastic element is part of the cover body.

### Claim 2 (depends on 1)

The apparatus according to claim 1, wherein there is a gap between the elastic element and other part of the cover body.

### Claim 3 (depends on 2)

The apparatus according to claim 2, wherein the elastic element is part of the cover edge of the cover body.

### Claim 4 (depends on 3)

The apparatus according to claim 3, wherein the elastic element is a rectangular structure, and the two long sides of the rectangular structure have a gap with other parts of the cover edge of the cover body, the short side is connected to the cover edge and the short side is exposed.

### Claim 5 (depends on 4)

The apparatus according to claim 4, wherein the inner surface of the elastic element on the exposed short side has a protrusive structure.

### Claim 6 (depends on 4)

The apparatus according to claim 4, wherein the outer surface of the elastic element on the exposed short side has a protrusive structure.

### Claim 7 (depends on 5)

The apparatus according to claim 5, wherein the protrusive structure has the same material as the elastic element, and the thickness of the protrusive structure is greater than that of the elastic element.

### Claim 8 (depends on 6)

The apparatus according to claim 6, wherein the elastic modulus of the protrusive structure is greater than the elastic modulus of the elastic element.

### Claim 9 (depends on 5)

The apparatus according to claim 5, wherein the non-elastic element is provided on an outer wall of the collection chamber, during the rotation and covering of the external thread of the collection chamber and the internal thread of the cover body, the non-elastic element contacts the protrusive structure on the inner surface of the elastic element to move relative to each other, to allow the elastic element to deform.

### Claim 10 (depends on 6)

The apparatus according to claim 6, wherein the non-elastic element is provided on an outer wall of the collection chamber, during the rotation and covering of the external thread of the collection chamber and the internal thread of the cover body, the non-elastic element contacts the protrusive structure on the outer surface of the elastic element, to allow the elastic element to deform.

### Claim 11 (depends on 1)

The apparatus according to claim 1, wherein the collection chamber has an external thread, and the cover body has an internal thread cooperating therewith, and the elastic element on the cover body does not have an internal thread.

### Claim 12 (depends on 9)

The apparatus according to claim 9, wherein the direction of deformation is away from the circumferential plane where the cover edge is located.

### Claim 13 (depends on 10)

The apparatus according to claim 10, wherein the direction of deformation is away from the circumferential plane where the cover edge is located.

### Claim 14 (depends on 9)

The apparatus according to claim 9, wherein the elastic element rebounds to strike the cup body to make a sound from the non-elastic element contacts the protrusive structure on the inner surface of the elastic element until the non-elastic element does not contact the protrusive structure on the inner surface of the elastic element.

### Claim 15 (depends on 10)

The apparatus according to claim 10, wherein the elastic element rebounds to strike the cup body to make a sound from the non-elastic element contacts the protrusive structure on the outer surface of the elastic element until the non-elastic element does not contact the protrusive structure on the outer surface of the elastic element.

### Claim 16 (depends on 14)

The apparatus according to claim 14, wherein the elastic element rebounds to strike the cup edge portion opposite to the elastic element to make a sound from the non-elastic element contacts the protrusive structure on the inner surface of the elastic element until the non-elastic element does not contact the protrusive structure on the inner surface of the elastic element.

### Claim 17 (depends on 15)

The apparatus according to claim 15, wherein the elastic element rebounds to strike the cup edge portion opposite to the elastic element to make a sound from the non-elastic element contacts the protrusive structure on the outer surface of the elastic element until the non-elastic element does not contact the protrusive structure on the outer surface of the elastic element.

### Claim 18 (depends on 1)

The apparatus according to claim 1, wherein the testing element is a drug testing element.

### Claim 19 (depends on 18)

The apparatus according to claim 18, wherein the testing element is a lateral flow test strip.

### Claim 20 (depends on 19)

The apparatus according to claim 19, wherein the lateral flow test strip is an immunoassay strip.
