# US 2019/0168016 A1 · Methods, compositions and apparatuses for treating psoriasis by phototherapy

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- Number: US 2019/0168016 A1
- Document ID: US20190168016A1
- Status: Published application
- Kind: A1
- Application number: 16/076,709
- Filed: 2017-02-09
- Published: 2019-06-06
- Earliest claimed: 2016-02-09
- Assignees: Luma Therapeutics, Inc.
- Applicants: Luma Therapeutics, Inc.
- Inventors: Evan R. ANDERSON; Adam MARTOS; Christopher Steven PELL
- Web page: https://patentgrep.com/patent/US20190168016A1

## CPC

- A61N 5/0616: {Skin treatment other than tanning}
- A61K 9/06: Ointments; Bases therefor; {Other semi-solid forms, e.g. creams, sticks, gels (composition of ointments, creams or gels A61K47/00)}
- A61K 35/04: Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
- A61N 5/06: using light
- A61P 17/00: Drugs for dermatological disorders
- A61P 17/06: Antipsoriatics
- A61N 2005/0627: {Dose monitoring systems and methods}
- A61N 2005/0645: {Applicators worn by the patient}
- A61N 2005/0652: {Arrays of diodes}
- A61N 2005/0661: {ultraviolet}
- A61N 2005/0667: {Filters}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

Compositions, methods and apparatuses for phototherapy to treat skin disorders. In particular, described herein are methods, compositions, phototherapy dressings for use with phototherapy UV light applicators (sources) and phototherapy UV light applicators to treat skin disorders such as psoriasis.

## Claims

### Claim at position 1

1-90. (canceled)

### Claim 91

A dressing system for treating a skin disorder, the system comprising:
a frame configured to be worn on a patient's skin, the frame having a highly adhesive bottom surface configured for multi-day wear, the frame further forming an open window region, and the frame comprising one or more attachments configured to couple with a UV light source, wherein the frame is UV blocking; and
a patch configured to be adhesively and removably attached to cover the open window region of the frame, the patch further comprising a vapor occlusive barrier and a therapeutic agent.

### Claim 92 (depends on 91)

The system of claim 91, wherein the therapeutic agent comprises a hydrogel within the patch.

### Claim 93 (depends on 91)

The system of claim 91, wherein the therapeutic agent comprises a coal tar or coal tar extract.

### Claim 94 (depends on 92)

The system of claim 92, wherein the patch further comprises a scrim layer coupling the hydrogel layer to the patch.

### Claim 95 (depends on 91)

The system of claim 91, further comprising a UV light source configured to magnetically couple to the plurality of attachments on the frame and deliver UV light through the window.

### Claim 96 (depends on 91)

The system of claim 91, wherein the frame comprises polyurethane.

### Claim 97 (depends on 91)

The system of claim 91, further comprising a unique identifier associated with the phototherapy dressing.

### Claim 98 (depends on 91)

The system of claim 91, further comprising a unique identifier associated with the phototherapy dressing, wherein the unique identifier is one or more of: an RFID tag, an optical code, a magnetic signature, or an alphanumeric code, a capacitance signature and a resistive signature.

### Claim 99

A dressing system for treating a skin disorder, the system comprising:
a frame configured to be worn on a patient's skin, the frame having a highly adhesive bottom surface configured for multi-day wear, the frame further forming an open window region through the frame, and the frame comprising one or more attachments, wherein the frame is UV blocking;
a patch configured to be removably attached to cover the open window region of the frame, the patch further comprising a vapor occlusive barrier and a therapeutic agent; and
a UV light source configured to attach to the frame via the one or more attachments.

### Claim 100 (depends on 99)

The system of claim 99, wherein the therapeutic agent comprises a coal tar or a coal tar extract.

### Claim 101 (depends on 99)

The system of claim 99, wherein the patch further comprises a scrim layer coupling a hydrogel layer to the patch.

### Claim 102 (depends on 99)

The system of claim 99, wherein the frame comprises polyurethane.

### Claim 103 (depends on 99)

The system of claim 99, further comprising a unique identifier associated with the phototherapy dressing.

### Claim 104 (depends on 99)

The system of claim 99, further comprising a unique identifier associated with the phototherapy dressing, wherein the unique identifier is one or more of: an RFID tag, an optical code, a magnetic signature, or an alphanumeric code, a capacitance signature and a resistive signature.

### Claim 105

A method of treating a skin disorder, the method comprising:
applying a frame to a patient's skin with an adhesive bottom configured for multi-day wear;
attaching a first patch to the frame over an open window on the frame, wherein the patch comprises a therapeutic agent;
wearing the patch so that the therapeutic agent contacts the skin;
removing the patch from the frame while the frame remains on the patient's skin;
attaching a UV light source to a plurality of attachment contacts on the frame to secure the UV lights source over the open window on the frame; and
delivering a therapeutic dose of UV light from the UV light source.

### Claim 106 (depends on 105)

The method of claim 105, further comprising attaching a second patch over the open window on the frame.

### Claim 107 (depends on 105)

The method of claim 105, wherein attaching the UV light source comprises magnetically attaching the UV light source.

### Claim 108 (depends on 105)

The method of claim 105, further comprising identifying a unique identifier associated with the frame prior to delivering the therapeutic dose of UV light.

### Claim 109 (depends on 105)

The method of claim 105, wherein attaching the first patch comprises adhesively attaching the first patch.

### Claim 110 (depends on 105)

The method of claim 105, wherein delivering the therapeutic dose comprises blocking at least some of the applied UV light by the frame.

### Claim 111 (depends on 105)

The method of claim 105, wherein attaching the first patch comprises adhesively attaching the first patch over the open window so that the first patch forms a vapor barrier relative to the patient's skin to reduce or prevent odor.