# US 2019/0167998 A1 · Method of treating a neurological disorder using network stimulation

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- Number: US 2019/0167998 A1
- Document ID: US20190167998A1
- Status: Published application
- Kind: A1
- Application number: 16/271,098
- Filed: 2019-02-08
- Published: 2019-06-06
- Earliest claimed: 2014-10-29
- Inventors: Dirk De Ridder
- Web page: https://patentgrep.com/patent/US20190167998A1

## CPC

- A61N 1/36082: {Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease}
- A61N 1/36139: {with automatic adjustment}
- A61N 1/0529: {Electrodes for brain stimulation}
- A61N 1/0551: {Spinal or peripheral nerve electrodes}
- A61N 1/36025: {for treating a mental or cerebral condition}
- A61N 1/36067: {Movement disorders, e.g. tremor or Parkinson disease (stimulating motor muscle A61N1/36003)}
- A61N 1/36171: {Frequency}
- A61N 1/36178: {Burst or pulse train parameters}
- A61N 1/36185: {Selection of the electrode configuration}
- A61N 1/36192: {Amplitude modulation}
- A61N 1/36196: {Frequency modulation}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

Methods are provided to treat a neurological disorder in a patient by adjusting connectivity between network nodes in a brain of patient using electrical stimulation. Connectivity between network nodes may be increased by synchronous stimulation at multiple network nodes depending upon the neurological disorder. Also, connectivity may be decreased by asynchronous or randomized stimulation at multiple network nodes depending upon the neurological disorder.

## Claims

### Claim 1

A method of treating a neurological disorder in a patient, comprising:
identifying a neural network in the brain of the patient related to the neurological disorder;
identifying at least two separate target sites in the neural network for stimulation;
providing one or more stimulation leads with electrodes positioned relative to the at least two separate target sites;
providing electrical stimulation to the at least two separate target sites to adjust functional connectivity between the at least two separate target sites to treat the neurological disorder.