# US 2019/0167925 A1 · Dry powder inhaler and inhalation actuated mechanism thereof

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- Number: US 2019/0167925 A1
- Document ID: US20190167925A1
- Status: Published application
- Kind: A1
- Application number: 16/269,031
- Filed: 2019-02-06
- Published: 2019-06-06
- Earliest claimed: 2014-06-30
- Assignees: Chiesi Farmaceutici S.p.A.
- Applicants: Chiesi Farmaceutici S.p.A.
- Inventors: Valerio Tampieri; Lorenzo Zuccheri; Emiliano Ilandi; Alice Campanini; Irene Pasquali; Patrick Gerard Linnane; Nicholas Lee Hawson; David Gale; Joanne Garrad
- Web page: https://patentgrep.com/patent/US20190167925A1

## CPC

- A61M 15/0021: {Mouthpieces therefor}
- A61M 15/0065: {Inhalators with dosage or measuring devices (A61M15/0028 takes precedence; dosage devices incorporated in aerosol cans B65D83/52)}
- A61M 15/0075: {on a disc}
- A61M 15/0091: {mechanically breath-triggered}
- A61M 15/0025: {with caps}
- A61M 2202/062: Desiccants
- A61M 2202/064: Powder
- A61M 2206/16: Rotating swirling helical flow, e.g. by tangential inflows
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A flap (20) for an inhalation actuated mechanism (18) of a powder inhaler (1) comprises a base member (29), a skirt structure (24) projecting from a surface of the base member (29), and a coupling portion (21) to be coupled to a resilient member (40′) of the inhalation actuated mechanism (18).

## Claims

### Claim at position 1

1-22. (canceled)

### Claim 23

A flap for an inhalation actuated mechanism of a powder inhaler, comprising:
a base member comprising a plate-shaped flat portion;
a skirt structure projecting upward from a surface of the plate-shaped flat portion of the base member; and
a coupling portion to be coupled to a resilient member of the inhalation actuated mechanism, wherein:
the skirt structure comprises first side wall portions, which substantially extend in a longitudinal direction of the base member,
a second side wall portion which extends between the first side wall portions in a width direction of the base member, and
the coupling portion projects from a lower surface of the plate-shaped flat portion of the base member downward.

### Claim 24 (depends on 23)

The flap according to claim 23,
wherein the base member comprises a shaft portion at a rear end of the flat portion, the shaft portion being provided to pivotably support the flap in the inhalation actuated mechanism.

### Claim 25 (depends on 23)

The flap according to claim 23,
wherein a front end of the flat portion is at least partly rounded.

### Claim 26 (depends on 23)

The flap according to claim 23,
wherein the flat portion has a first straight longitudinal side and a second straight longitudinal side, the first and second longitudinal sides being connected by a combination of a straight front end portion and a rounded front end portion.

### Claim 27 (depends on 26)

The flap according to claim 26,
wherein a length of the first longitudinal side is shorter than a length of the second longitudinal side.

### Claim 28 (depends on 23)

The flap according to claim 23,
wherein the second side wall portion comprises an elongate thickening extending from the base member in a middle portion of the second side wall portion.

### Claim 29 (depends on 23)

The flap according to claim 23,
wherein the skirt structure comprises two of the first side wall portions which are spaced from one another in the width direction of the base member and are wedge-shaped such that a height of the first side wall portions gradually increases from a front end of the base member towards a rear end of the base member.

### Claim 30 (depends on 23)

The flap according to claim 23,
wherein the second side wall portion is inclined towards a rear end of the base member.

### Claim 31 (depends on 23)

The flap according to claim 23,
wherein the first side wall portions extend along the first and second longitudinal sides of the flat portion of the base member.

### Claim 32 (depends on 31)

The flap according to claim 31,
wherein the first side wall portion, which extends along the first longitudinal side of the flat portion of the base member, is angled such that a part thereof extends substantially parallel to the straight front end portion of the base member.

### Claim 33 (depends on 23)

The flap according to claim 23,
wherein the coupling portion for the resilient member of the inhalation actuated mechanism extends from a surface of the base member downward which is opposite to the surface from which the skirt structure projects upward.

### Claim 34 (depends on 23)

The flap according to claim 23,
wherein the flap comprises a projection that projects from a shaft portion of the flap backwards; and
wherein the projection is designed such that it acts as a counterweight upon a rotation of the flap in the inhalation actuated mechanism.

### Claim 35 (depends on 34)

The flap according to claim 34,
wherein the projection and the coupling portion are spaced in a width direction of the flap and extend substantially parallel to one another.

### Claim 36 (depends on 22)

A powder inhaler, comprising:
a container for storing a powdered medicament;
a metering member having a dosing recess to be filled with a dose of the powdered medicament from the container;
a mouthpiece being in communication with an inhalation channel for enabling inhalation of the dose of the powdered medicament contained in the dosing recess of the metering member; and
an inhalation actuated mechanism which is coupled to a protective member for the dosing recess of the metering member such that, if the protective member is in a closed position in which it at least partly covers the dosing recess, the inhalation actuated mechanism causes the protective member to move to an open position, in which the protective member does not cover the dosing recess, if an inhalation suction force exerted by a user on the inhalation channel exceeds a predetermined value,
wherein the inhalation actuated mechanism comprises the flap according to claim 22.

### Claim 37 (depends on 36)

The powder inhaler according to claim 36,
wherein the flap is arranged such that it is pivotable between a first position and a second position, wherein the flap is coupled to the protective member such that, if there is an inhalation suction force exceeding the predetermined value, the flap is moved from the first position to the second position, thereby causing the protective member to move from the closed position to the open position.

### Claim 38 (depends on 37)

The powder inhaler according to claim 37,
wherein the inhalation actuated mechanism comprises a resilient member which is tensioned by a movement of the metering member from a filling position, in which the dosing recess is in alignment with an opening of the container so as to be filled with the dose of the powdered medicament, to an inhalation position, in which the dosing recess is in alignment with the inhalation channel, wherein the resilient member is allowed to discharge upon a movement of the metering member from the inhalation position to the filling position;
wherein the resilient member is arranged such that it holds the flap in its first position if the resilient member is discharged, while the resilient member releases the flap if the resilient member is tensioned, so as to allow the flap to be moved from its first position to its second position by the inhalation suction force exceeding the predetermined value.

### Claim 39 (depends on 38)

The powder inhaler according to claim 38,
wherein the inhalation actuated mechanism comprises a coupling member coupling the flap to the protective member with the resilient member being coupled to the coupling member; and
wherein the coupling member comprises a portion which is held by the flap when it is in its first position, while the portion of the coupling member is released by a movement of the flap from its first position to its second position.

### Claim 40 (depends on 39)

The powder inhaler according to claim 39,
wherein the resilient member is a spring attached to a shaft-like portion of the coupling member.

### Claim 41 (depends on 39)

The powder inhaler according to claim 39,
wherein the inhalation actuated mechanism comprises a further resilient member which is mounted on a shaft-like portion of the coupling member.

### Claim 42 (depends on 41)

The powder inhaler according to claim 41,
wherein the further resilient member is a spring mounted on the shaft-like portion of the coupling member at an opposite side with respect to the resilient member.

### Claim 43 (depends on 42)

The powder inhaler according to claim 42,
wherein the further resilient member has a first end coupled to the coupling member and a second end coupled to a chassis of the powder inhaler.
