Therapeutic combinations to treat red blood cell disorders
AssigneeHartis-Pharma SA
InventorsJOSEPH ERIC NIESOR, RENEE BENGHOZI, FRANCOIS LAMOUR
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Abstract
The present invention is related to a combination useful in the prevention and/or treatment of red blood cell disorders, in particular, acute and chronic complications associated with red blood cell dysfunction, increased red blood cell cholesterol and decreased plasma levels of lipophilic antioxidant (sickle cell disease, thalassemia, diabetes). The invention in particular relates to pharmaceutical formulations, regimens, methods of treatment and uses thereof.
Claims20
1-20. (canceled)
A method of preventing and/or treating a disease or disorder characterized by acute and chronic complications associated with red blood cell dysfunction, increased red blood cell cholesterol and/or decreased plasma levels of lipophilic antioxidant, said method comprising administering at least one agent increasing HDL activity in combination with at least one liposoluble antioxidant or a mixture thereof to a subject in need thereof.
A pharmaceutical composition comprising of at least one compound increasing HDL activity and at least one liposoluble antioxidant or a mixture thereof and a pharmaceutically acceptable carrier, diluent or excipient thereof.
Dependencies are inferred from the claim text.