# US 2019/0167751 A1 · Dietary supplement compositions

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- Number: US 2019/0167751 A1
- Document ID: US20190167751A1
- Status: Published application
- Kind: A1
- Application number: 16/198,121
- Filed: 2018-11-21
- Published: 2019-06-06
- Earliest claimed: 2015-01-02
- Assignees: Melaleuca, Inc.
- Applicants: Melaleuca, Inc.
- Inventors: Alexander B. Rabovsky; Stephanie Y. Nielson
- Web page: https://patentgrep.com/patent/US20190167751A1

## CPC

- A61K 36/68: Plantaginaceae (Plantain Family)
- A23L 33/10: using additives (addition of substantially indigestible substances A23L33/21)
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A23L 33/15: Vitamins
- A23L 33/175: Amino acids
- A61K 9/20: Pills, tablets, {discs, rods (A61K9/0004, A61K9/0007, A61K9/0056, A61K9/0065 take precedence; for reconstitution of a drink A61K9/0095)}
- A61K 9/48: Preparations in capsules, e.g. of gelatin, of chocolate {(A61K9/0004 takes precedence; bite capsules A61K9/0056)}
- A61K 31/12: Ketones
- A61K 31/14: Quaternary ammonium compounds, e.g. edrophonium, choline (betaines A61K31/205)
- A61K 31/221: with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
- A61K 31/355: Tocopherols, e.g. vitamin E
- A61K 31/4748: forming part of bridged ring systems (strychnine A61K31/475; morphinan derivatives A61K31/485)
- A61K 31/519: ortho- or peri-condensed with heterocyclic rings
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)

## Abstract

This document provides dietary supplement compositions. For example, dietary supplement compositions having an acetylcholinesterase inhibitor (e.g., huperzine A), a Bacopa monnieri extract, acetyl-L-carnitine or acetyl CoA, and a curcuminoid (e.g., curcumin) are provided.

## Claims

### Claim 1

A composition comprising:
(a) between about 0.01 mg and about 8 mg of huperzine A,
(b) between about 100 mg and about 3000 mg of acetyl-L-carnitine,
(c) between about 25 mg to about 500 mg of Bacopa monnieri, and
(d) between about 10 mg and about 500 mg of curcumin.

### Claim 2 (depends on 1)

The composition of claim 1, wherein said composition further comprises between about 10 IU and about 800 IU of Vitamin E.

### Claim 3 (depends on 1)

The composition of claim 1, wherein said composition further comprises between about 0.14 mg and about 20 mg of folic acid.

### Claim 4 (depends on 1)

The composition of claim 1, wherein said composition further comprises between about 0.3 mg and 1.0 mg of folic acid.

### Claim 5 (depends on 1)

The composition of claim 1, wherein said composition is in the form of a tablet or capsule.

### Claim 6 (depends on 1)

The composition of claim 1, wherein said composition is in the form of multiple tablets or capsules.

### Claim 7

A composition comprising:
(a) between about 0.01 and about 0.40 mg of huperzine A,
(b) between about 200 mg and about 3000 mg of acetyl-L-carnitine,
(c) between about 50 mg to about 1000 mg of Bacopa monnieri,
(d) between about 25 mg and about 400 mg of curcumin,
(e) between about 100 IU and about 800 IU of Vitamin E, and
(f) between about 0.1 mg and about 10 mg of folic acid.

### Claim 8

A composition comprising:
(a) at least about 0.01 mg of an acetylcholinesterase inhibitor,
(b) at least one of acetyl-L-carnitine and acetyl CoA,
(c) at least about 25 mg of Bacopa monnieri,
(d) at least about 10 mg of a curcuminoid,
(e) at least about 10 IU of Vitamin E, and
(f) at least about 0.1 mg of folic acid.