# US 2019/0167745 A1 · Composition containing a bean extract for improving blood circulation and vascular health and method for improving blood circulation and vascular health

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 2019/0167745 A1
- Document ID: US20190167745A1
- Status: Published application
- Kind: A1
- Application number: 16/266,658
- Filed: 2019-02-04
- Published: 2019-06-06
- Earliest claimed: 2009-05-26
- Assignees: Amorepacific Corporation
- Applicants: Amorepacific Corporation
- Inventors: Hyun J. Shin; Jin Kwan KIM; Chae Wook KIM; Kyung Mi JOO; Yeon Su JEONG; Kyung Min LIM; Dae-Bang SEO; Yung Hyup JOO; Sang Jun LEE; Young-Ho PARK
- Web page: https://patentgrep.com/patent/US20190167745A1

## CPC

- A61K 36/48: Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A23L 2/52: Adding ingredients (adding preservatives A23B70/10)
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A61P 3/04: Anorexiants; Antiobesity agents
- A61P 3/06: Antihyperlipidemics
- A61P 3/10: for hyperglycaemia, e.g. antidiabetics
- A61P 7/00: Drugs for disorders of the blood or the extracellular fluid
- A61P 7/02: Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A61P 7/06: Antianaemics
- A61P 9/00: Drugs for disorders of the cardiovascular system
- A61P 9/08: Vasodilators for multiple indications
- A61P 9/10: for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A61P 9/12: Antihypertensives
- A61P 9/14: Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- A61P 25/06: Antimigraine agents
- A61K 2236/333: using mixed solvents, e.g. 70% EtOH
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention relates to a composition containing a bean extract extracted by low-concentration, low-grade alcohol or fractions thereof. The composition exhibits excellent effects in improving blood circulation, improving obesity, and preventing diabetes, hyperlipidemia and the like, and exhibits the effects of alleviating or treating the symptoms of diabetes, hyperlipidemia, and the like. The present invention also relates to a method for improving blood circulation and vascular health.

## Claims

### Claim 1

A method for improving blood circulation of a subject, comprising administering to the subject an effective amount of a bean extract extracted with a C1-C5 alcohol with a concentration of 1-70% (v/v) or a fraction thereof, wherein the bean extract or the fraction thereof suppresses blood clotting in the subject,
wherein the bean is at least one selected from a group consisting of Seoritae, Seomoktae and field bean.

### Claim at position 2

2-14. (canceled)

### Claim 15 (depends on 1)

The method according to claim 1, wherein the C1-C5 alcohol is ethanol.

### Claim 16 (depends on 1)

The method according to claim 1, wherein the concentration of the C1-C5 alcohol is 5-25% (v/v).

### Claim 17 (depends on 1)

The method according to claim 1, wherein the bean extract or the fraction thereof comprises adenosine.

### Claim 18 (depends on 16)

The method according to claim 16, wherein the adenosine is included in an amount of 0.01-1.0 wt % based on the weight of the bean extract or the fraction thereof.

### Claim 19 (depends on 1)

The method according to claim 1, wherein the bean extract or the fraction thereof improves vascular health.

### Claim 20 (depends on 1)

The method according to claim 1, wherein the blood clotting is a platelet aggregation induced by a collagen.

### Claim 21 (depends on 1)

The method according to claim 1, wherein the method is for preventing, alleviating or treating obesity, diabetes, stroke, cerebral hemorrhage, arteriosclerosis, angina, myocardial infarction, hypertension, anemia, migraine or hyperlipidemia.