# US 2019/0167620 A1 · Therapeutic compositions and methods

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- Number: US 2019/0167620 A1
- Document ID: US20190167620A1
- Status: Published application
- Kind: A1
- Application number: 15/829,798
- Filed: 2017-12-01
- Published: 2019-06-06
- Earliest claimed: 2017-12-01
- Assignees: Innovus Pharmaceuticals, Inc.
- Applicants: Innovus Pharmaceuticals, Inc.
- Inventors: Bassam Damaj
- Web page: https://patentgrep.com/patent/US20190167620A1

## CPC

- A61K 31/198: Alpha-amino acids, e.g. alanine or edetic acid [EDTA] (betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00)
- A61K 9/48: Preparations in capsules, e.g. of gelatin, of chocolate {(A61K9/0004 takes precedence; bite capsules A61K9/0056)}
- A61K 9/4875: {Compounds of unknown constitution, e.g. material from plants or animals (oils, fats, waxes, shellac A61K9/4858)}
- A61K 31/405: Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A61K 31/4415: Pyridoxine, i.e. Vitamin B6 (pyridoxal phosphate A61K31/675)
- A61K 31/443: containing a five-membered ring with oxygen as a ring hetero atom
- A61K 31/4545: containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A61K 33/00: Medicinal preparations containing inorganic active ingredients
- A61K 33/08: Oxides; Hydroxides
- A61K 36/67: Piperaceae (Pepper family), e.g. Jamaican pepper or kava
- A61K 47/02: Inorganic compounds
- A61K 47/38: Cellulose; Derivatives thereof
- A61P 15/10: for impotence
- A61K 9/4866: {Organic macromolecular compounds}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The invention provides compositions and unit dosage forms that are effective to improve sexual performance. Such compositions and unit dosage forms are useful to increase duration of sexual intercourse, satisfaction with sexual intercourse, and improve erectile function in men.

## Claims

### Claim 1

A dosage form suitable for oral administration in a human comprising Vitamin B6, magnesium oxide, L-tyrosine, DL-phenylalanine, L-trypotphan, L-glutamine, AstraGin®, and piperylpiperidine.

### Claim 2 (depends on 1)

The dosage form of claim 1 that further comprises one or more excipients selected from hydroxypropyl methylcellulose, rice concentrate, and silica.

### Claim 3

A unit dosage form suitable for oral administration in a human comprising:
about 800 μg Vitamin B6;
about 8 mg Mg+2, from magnesium oxide;
about 400 mg L-tyrosine;
about 400 mg DL-phenylalanine;
about 100 mg L-tryptophan;
about 52 mg L-glutamine;
about 20 mg AstraGin®; and
about 20 mg 1-piperylpiperidine.

### Claim 4

(canceled)

### Claim 5

(canceled)

### Claim 6 (depends on 3)

The unit dosage form of claim 3 that is formulated as a capsule.

### Claim at position 7

7-12. (canceled)