# US 2019/0167546 A1 · Oral Care Compositions > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2019/0167546 A1 - Document ID: US20190167546A1 - Status: Published application - Kind: A1 - Application number: 16/267,424 - Filed: 2019-02-05 - Published: 2019-06-06 - Earliest claimed: 2015-12-30 - Assignees: Colgate-Palmolive Company - Applicants: Colgate-Palmolive Company - Inventors: Shiri Nawrocki; Viktor DUBOVOY; Long PAN; Zhigang HAO; Nihal DOGU - Web page: https://patentgrep.com/patent/US20190167546A1 ## CPC - A61K 8/24: Phosphorous; Compounds thereof - A61K 8/19: containing inorganic ingredients - A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na5P3O10), and oral care compositions comprising the complex and uses thereof. ## Claims ### Claim 1 An oral care composition comprising an aqueous soluble tin phosphate complex formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt. ### Claim 2 (depends on 1) The composition of claim 1, wherein the tripolyphosphate salt is sodium tripolyphosphate (Na5P3O10). ### Claim 3 (depends on 1) The composition of claim 1, wherein the complex is formed in situ in an aqueous solution and combined with the composition. ### Claim 4 (depends on 3) The composition of claim 3, wherein the complex is isolated from the aqueous solution in solid form and combined with the composition. ### Claim 5 (depends on 1) The composition of claim 1, wherein the complex is lyophilized and combined with the composition. ### Claim 6 (depends on 1) The composition of claim 1, wherein the complex is isolated with an anti-solvent and combined with the composition. ### Claim 7 (depends on 1) The composition of claim 1, wherein the complex is present in an amount of 2 to 30 weight % by weight of the composition. ### Claim 8 (depends on 1) The composition of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and the tripolyphosphate salt in a molar ratio of 1P:1Sn to less than 15P:1Sn. ### Claim 9 (depends on 1) The composition of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and the tripolyphosphate salt in a molar ratio of greater than 2P:1Sn to less than 10P:1Sn. ### Claim 10 (depends on 1) The composition of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and the tripolyphosphate salt in a molar ratio of 2P:1Sn to 5P:1Sn. ### Claim 11 (depends on 1) The composition of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and the tripolyphosphate salt in a molar ratio of 3P:1Sn to 5P:1Sn. ### Claim 12 (depends on 1) The composition of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and the tripolyphosphate salt in a molar ratio of 5P:1Sn. ### Claim 13 (depends on 1) The composition of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and sodium tripolyphosphate in a molar ratio of 1P:1Sn to less than 15P:1Sn. ### Claim 14 (depends on 1) The composition of any one of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and sodium tripolyphosphate in a molar ratio of greater than 2P:1Sn to less than 10P:1Sn. ### Claim 15 (depends on 1) The composition of any one of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and sodium tripolyphosphate in a molar ratio of 2P:1Sn to 5P:1Sn. ### Claim 16 (depends on 1) The composition of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and sodium tripolyphosphate in a molar ratio of 3P:1Sn to 5P:1Sn. ### Claim 17 (depends on 1) The composition of claim 1, wherein the complex is formed from tin (II) fluoride or tin (II) chloride and sodium tripolyphosphate in a molar ratio of 5P:1Sn. ### Claim 18 (depends on 1) The composition of claim 1, wherein the complex is formed from a mixture comprising 1 to 10 weight % tin (II) fluoride or tin (II) chloride by weight of the mixture and 1 to 20 weight % tripolyphosphate salt by weight of the mixture. ### Claim 19 (depends on 1) The composition of claim 1, wherein the complex is formed from a mixture comprising 1 to 10 weight % tin (II) fluoride or tin (II) chloride by weight of the mixture and 1 to 10 weight % tripolyphosphate salt by weight of the mixture. ### Claim 20 (depends on 1) The composition of claim 1, wherein the complex is formed from a mixture comprising 1 to 10 weight % tin (II) fluoride or tin (II) chloride by weight of the mixture and 1 to 20 weight % sodium tripolyphosphate by weight of the mixture. ### Claim 21 (depends on 1) The composition of claim 1, wherein the complex is formed from a mixture comprising 1 to 10 weight % tin (II) fluoride or tin (II) chloride by weight of the mixture and 1 to 10 weight % sodium tripolyphosphate by weight of the mixture. ### Claim 22 (depends on 1) The composition of claim 1, wherein the composition comprises tin (II) fluoride. ### Claim 23 (depends on 1) The composition of claim 1, wherein the composition comprises tin (II) chloride. ### Claim 24 (depends on 1) The composition of claim 1, wherein the composition comprises an aqueous solution. ### Claim 25 (depends on 1) The composition of claim 1 further comprising more than 20 weight % water by weight of the composition. ### Claim 26 (depends on 1) The composition of claim 1, wherein the composition is a mouthwash. ### Claim 27 (depends on 1) The composition of claim 1 for use to reduce dentinal hypersensitivity. ### Claim 28 (depends on 1) A method to reduce or inhibit dentinal hypersensitivity, dental caries, gingivitis, or plaque in a person in need thereof comprising applying an effective amount of an oral care composition as claimed in claim 1 to teeth of the person.