# US 2019/0167333 A1 · Tumor ablation system

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- Number: US 2019/0167333 A1
- Document ID: US20190167333A1
- Status: Published application
- Kind: A1
- Application number: 16/269,997
- Filed: 2019-02-07
- Published: 2019-06-06
- Earliest claimed: 2015-01-09
- Assignees: Medtronic Holding Company SàRl
- Applicants: Medtronic Holding Company SàRl
- Inventors: Calin Druma
- Web page: https://patentgrep.com/patent/US20190167333A1

## CPC

- A61B 18/04: by heating (by applying electromagnetic radiation A61B18/18)
- A61B 17/8805: {for introducing fluid filler into bone or extracting it (A61B17/7097, A61B17/8833 take precedence)}
- A61B 17/8825: {characterised by syringe details (A61B17/8822, A61B17/8827 take precedence)}
- A61B 17/8855: {inflatable, e.g. kyphoplasty balloons}
- A61B 18/18: by applying electromagnetic radiation, e.g. microwaves
- A61B 18/1815: {using microwaves}
- A61B 2017/00057: {Light}
- A61B 2017/00084: {Temperature}
- A61B 2018/00023: {closed, i.e. without wound contact by the fluid}
- A61B 2018/00166: {Multiple lumina}
- A61B 2018/0022: {Balloons}
- A61B 2018/00232: {having an irregular shape}
- A61B 2018/0025: {Multiple balloons}
- A61B 2018/00339: {Spine, e.g. intervertebral disc}
- A61B 2018/00565: {Bone}
- A61B 2018/00577: {Ablation}
- A61B 2018/00791: {Temperature}
- A61B 2018/00809: {measured thermochromatically}
- A61B 2018/00821: {measured by a thermocouple}
- A61B 2018/046: {in liquid form}
- A61B 2018/1823: {Generators therefor}
- A61B 2018/183: {characterised by the type of antenna}
- A61B 2018/1861: {with an instrument inserted into a body lumen or cavity, e.g. a catheter}
- A61B 2018/1869: {with an instrument interstitially inserted into the body, e.g. needles}
- A61B 2018/1892: {Details of electrical isolations of the antenna}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A system for use in tumor ablation. The tumor ablation system includes a microwave antenna which has a channel along the length thereof. There are two ports proximate the proximal end of the microwave antenna. The first port is an energy port configured to connect the antenna to an energy source. The second port is a fluid port configured to connect the channel to a fluid delivery mechanism. The system also includes an inflatable balloon configured to be attached to a distal end of the antenna. The channel permits fluid access from the fluid port to an interior of the balloon for inflation thereof.

## Claims

### Claim 1

A method of tumor ablation, the method comprising:
making an incision in skin of a patient;
creating an opening in a bone having a tumor;
inserting a portion of a microwave antenna system into the opening in the bone, the antenna system including a microwave antenna having a proximal end, a distal end opposite the proximal end, a length between the proximal end and the distal end, a first conductor terminating at an end at the distal end of the antenna, a second conductor terminating at an end positioned between the proximal end and the distal end of the antenna, and a first channel and a second channel extending along at least a portion of the length of the antenna along portions of the first conductor and the second conductor, an energy port proximate the proximal end to connect the antenna to an energy source, a fluid port proximate the proximal end to connect the first channel and the second channel to a fluid delivery mechanism, an inflatable balloon attached to the antenna adjacent the end of the second conductor and having an interior fluidly communicating with the first channel and the second channel, and a flexible member connecting the first conductor to an end portion of the balloon in the interior thereof;
positioning at least the balloon adjacent the tumor;
introducing a fluid through the fluid port and through the first channel and the second channel to inflate the balloon causing the balloon to apply pressure to the tumor;
applying energy through the energy port to one of the first conductor and the second conductor to heat the fluid in the balloon and heat the tumor;
constraining movement of the end portion of the balloon relative to the first conductor using the flexible member; and
removing the microwave antenna system from the patient.

### Claim 2 (depends on 1)

The method of claim 1, further comprising creating a cavity in the bone via the inflation of the balloon, and, after removal of the microwave antenna system from the patient, filling the opening and the cavity with bone cement.

### Claim 3 (depends on 1)

The method of claim 1, wherein the energy is microwave excitation.

### Claim 4 (depends on 1)

The method of claim 1, wherein the fluid is saline.

### Claim 5 (depends on 1)

The method of claim 1, further comprising monitoring the temperature of the tumor.

### Claim 6 (depends on 5)

The method of claim 5, further comprising heating the tumor to at least 50 degrees Celsius.

### Claim 7 (depends on 1)

The method of claim 1, wherein the bone is a vertebral body.

### Claim 8 (depends on 1)

The method of claim 1, wherein the creating the opening and inserting the portion of the microwave antenna system are performed through a cannula.

### Claim 9 (depends on 1)

The method of claim 1, further comprising:
making a second incision in the skin of the patient;
creating a second opening in the bone;
inserting a portion of a second microwave antenna system identical to the microwave antenna system into the second opening in the bone;
creating a second cavity in the bone using the second microwave antenna system;
removing the second microwave antenna system from the patient; and
after removal of the second microwave antenna system from the patient, filling the second opening and the second cavity in the bone with bone cement.

### Claim 10 (depends on 9)

The method of claim 9, further comprising:
applying energy to the second antenna to heat the second fluid.

### Claim 11 (depends on 9)

The method of claim 9, wherein the creating the second opening and inserting the portion of the second microwave antenna system are performed through a second cannula.

### Claim 12 (depends on 1)

The method of claim 1, wherein the first conductor is positioned at least partially within the second conductor.

### Claim 13 (depends on 12)

The method of claim 12, wherein the first channel and the second channel are positioned on opposite sides of the first conductor.

### Claim 14 (depends on 1)

The method of claim 1, wherein the balloon includes a proximal end and a distal end, the proximal end of the balloon being attached to the antenna adjacent the end of the second conductor, and the end portion of the balloon being at the distal end of the balloon.

### Claim 15 (depends on 14)

The method of claim 14, wherein the balloon has a maximum length between the first end and the second end, and the flexible member extends over half the maximum length of the balloon.

### Claim 16

A method of tumor ablation, the method comprising:
making an incision in skin of a patient;
creating an opening in a bone having a tumor;
inserting a portion of a microwave antenna system into the opening in the bone, the antenna system including a microwave antenna having a proximal end, a distal end opposite the proximal end, a length between the proximal end and the distal end, a first conductor terminating at an end at the distal end of the antenna, a second conductor terminating at an end positioned between the proximal end and the distal end of the antenna, and at least one channel extending along at least a portion of the length of the antenna along portions of the first conductor and the second conductor, an energy port proximate the proximal end to connect the antenna to an energy source, a fluid port proximate the proximal end to connect the at least one channel to a fluid delivery mechanism, an inflatable balloon attached to the antenna adjacent the end of the second conductor and having an interior fluidly communicating with the at least one channel, and a flexible member connecting the first conductor to an end portion of the balloon in the interior thereof;
positioning at least the balloon adjacent the tumor;
introducing a fluid through the fluid port and through the at least one channel to inflate the balloon causing the balloon to apply pressure to the tumor and create a cavity in the bone;
applying energy through the energy port to one of the first conductor and the second conductor to heat the fluid in the balloon and heat the tumor;
constraining movement of the end portion of the balloon relative to the first conductor using the flexible member; and
removing the microwave antenna system from the patient.

### Claim 17 (depends on 16)

The method of claim 16, wherein the balloon includes a proximal end and a distal end, the proximal end of the balloon being attached to the antenna adjacent the end of the second conductor, and the end portion of the balloon being at the distal end of the balloon.

### Claim 18 (depends on 17)

The method of claim 17, wherein the balloon has a maximum length between the first end and the second end, and the flexible member extends over half the maximum length of the balloon.

### Claim 19

A method of tumor ablation, the method comprising:
making an incision in skin of a patient;
creating an opening in a bone having a tumor;
inserting a portion of a microwave antenna system into the opening in the bone, the antenna system including a microwave antenna having a proximal end, a distal end opposite the proximal end, a length between the proximal end and the distal end, a first conductor terminating at an end at the distal end of the antenna, and a second conductor terminating at an end positioned between the proximal end and the distal end of the antenna, an energy port proximate the proximal end to connect the antenna to an energy source, a fluid port proximate the proximal end to connect the at least one channel to a fluid delivery mechanism, an inflatable balloon attached to the antenna adjacent the end of the second conductor, and a flexible member connecting the first conductor to an end portion of the balloon in the interior thereof;
positioning at least the balloon adjacent the tumor;
inflating the balloon to cause the balloon to apply pressure to the tumor and create a cavity in the bone;
applying energy through the energy port to one of the first conductor and the second conductor to heat the tumor;
constraining movement of the end portion of the balloon relative to the first conductor using the flexible member; and
removing the microwave antenna system from the patient.

### Claim 20 (depends on 19)

The method of claim 19, wherein the balloon includes a proximal end and a distal end, the proximal end of the balloon being attached to the antenna adjacent the end of the second conductor, and the end portion of the balloon being at the distal end of the balloon.
