# US 2019/0167242 A1 · Devices and methods for closing a left atrial appendage > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2019/0167242 A1 - Document ID: US20190167242A1 - Status: Published application - Kind: A1 - Application number: 16/200,455 - Filed: 2018-11-26 - Published: 2019-06-06 - Earliest claimed: 2017-12-04 - Assignees: Edwards Lifesciences Corporation - Applicants: Edwards Lifesciences Corporation - Inventors: Stanton J. Rowe; Robert S. Schwartz - Web page: https://patentgrep.com/patent/US20190167242A1 ## CPC - A61B 17/0057: {Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009)} - A61B 17/064: Surgical staples, {i.e. penetrating the tissue} - A61B 17/0643: {with separate closing member, e.g. for interlocking with staple} - A61B 17/12: for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord - A61B 17/12031: {complete occlusion} - A61B 17/12122: {within the heart (for closing a cardiac septal defect A61B17/0057)} - A61B 17/12172: {having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526)} - A61B 2017/00336: {with a protective sleeve, e.g. retractable or slidable} - A61B 2017/00349: {Needle-like instruments having hook or barb-like gripping means, e.g. for grasping suture or tissue (A61B17/06066 takes precedence)} - A61B 2017/00592: {Elastic or resilient implements} - A61B 2017/00623: {Introducing or retrieving devices therefor} - A61B 2017/00632: {Occluding a cavity, i.e. closing a blind opening} - A61B 2017/00862: {elastic or resilient} - A61B 2017/0641: {having at least three legs as part of one single body} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract Disclosed herein are devices and methods for closing a left atrial appendage (LAA) that use an expandable disk having a deployment anchor and a plurality of peripheral hooks. The LAA closure devices are configured to expand to a diameter that is larger than a diameter of the LAA ostium. The deployment anchor attaches the disk to the tissue of the LAA that is everted or invaginated. The expandable disk causes the everted or invaginated LAA to expand and flatten within the left atrium of the heart. The peripheral hooks pierce the tissue of the LAA and engage the left atrial wall to close the LAA predominantly with its own tissue. ## Claims ### Claim 1 A device for closing a left atrial appendage, the device comprising: an expandable disk having an expanded diameter that is larger than 10 mm; a deployment anchor attached to the expandable disk near a center of a first side of the expandable disk, the deployment anchor configured to puncture a tissue of a left atrial appendage and to anchor the expandable disk to the tissue of the left atrial appendage; and a plurality of closure anchors attached to the expandable disk near a periphery of the expandable disk, the plurality of closure anchors configured to secure the expandable disk to tissue of a left atrium, wherein the device is configured for delivery in a compact state and expands to an expanded state to cause an everted left atrial appendage to assume a size that is larger than an ostium of the left atrial appendage. ### Claim 2 (depends on 1) The device of claim 1 wherein the closure anchors are attached to the expandable disk on a second side of the expandable disk, the second side opposite the first side. ### Claim 3 (depends on 1) The device of claim 1 wherein the closure anchors are attached to the expandable disk on the first side of the expandable disk. ### Claim 4 (depends on 1) The device of claim 1 wherein the device is configured to assume a compact state for delivery and a deployed state for deployment for closing a left atrial appendage. ### Claim 5 (depends on 5) The device of claim 5 wherein the compact state comprises reducing a diameter of the expandable disk to fit within a sheath of a delivery system. ### Claim 6 (depends on 5) The device of claim 5 wherein the deployed state comprises the expandable disk assuming a size and shape such that the expanded diameter is larger than a typical ostium of a left atrial appendage. ### Claim 7 (depends on 1) The device of claim 1 wherein the expandable disk includes radial supports. ### Claim 8 (depends on 7) The device of claim 7 wherein individual closure anchors are coupled to ends of corresponding radial supports. ### Claim 9 (depends on 1) A left atrial appendage closure kit including the device of claim 1 and a delivery system having a retractable sheath configured to house the expandable disk in a compact state. ### Claim 10 (depends on 9) The kit of claim 9 wherein the delivery system the sheath is configured to be pulled back during operation to release the expandable disk in the compact state such that the expandable disk expands to assume a deployed state. ### Claim 11 A method for closing a left atrial appendage, the method comprising: anchoring an expandable disk to an everted tissue wall of the left atrial appendage with a deployment anchor attached to the expandable disk; expanding the expandable disk to expand the everted tissue wall to cover an ostium of the left atrial appendage; and securing the everted tissue wall of the left atrial appendage to a wall of the left atrium with a plurality of closure anchors. ### Claim 12 (depends on 11) The method of claim 11 further comprising everting the tissue wall of the left atrial appendage so that the tissue wall of the left atrial appendage is within the left atrium. ### Claim 13 (depends on 12) The method of claim 12 wherein everting the tissue wall comprises using a rounded catheter tip from a location external to a heart to evert the left atrial appendage. ### Claim 14 (depends on 12) The method of claim 12 wherein everting the tissue wall comprises using a rounded catheter tip from a location within the left atrium to evert the left atrial appendage. ### Claim 15 (depends on 11) The method of claim 11 wherein the method is performed during a minimally invasive procedure. ### Claim 16 (depends on 11) The method of claim 11 wherein the method is performed during open heart surgery. ### Claim 17 A device for closing a left atrial appendage, the device comprising: an expandable disk having an expanded diameter that is larger than 10 mm; a deployment anchor attached to the expandable disk near a center of a first side of the expandable disk, the deployment anchor configured to puncture a tissue of a left atrial appendage and to anchor the expandable disk to the tissue of the left atrial appendage; a securing ring forming an annulus; and a plurality of closure anchors attached to the securing ring, the plurality of closure anchors configured to secure the expandable disk to tissue of a left atrium, wherein the expandable disk is configured for delivery in a compact state and expands to an expanded state to cause an everted left atrial appendage to assume a size that is larger than an ostium of the left atrial appendage. ### Claim 18 (depends on 17) The device of claim 17 wherein the expandable disk includes radial supports. ### Claim 19 (depends on 17) The device of claim 17 wherein the plurality of closure anchors comprises less than or equal to 6 anchors. ### Claim 20 (depends on 17) The device of claim 17 wherein the plurality of closure anchors comprises at least 2 anchors.