# US 2019/0167238 A1 · Biopsy device with applied imaging > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2019/0167238 A1 - Document ID: US20190167238A1 - Status: Published application - Kind: A1 - Application number: 16/208,814 - Filed: 2018-12-04 - Published: 2019-06-06 - Earliest claimed: 2017-12-05 - Assignees: Devicor Medical Products, Inc. - Applicants: Devicor Medical Products, Inc. - Inventors: Bryan R. Keller; Patrick A. Mescher - Web page: https://patentgrep.com/patent/US20190167238A1 ## CPC - A61B 10/0275: {with sample notch, e.g. on the side of inner stylet} - A61B 10/0096: {Casings for storing test samples (A61B10/0038, A61B10/0045 take precedence; preservation of living parts of the human or animal body A01N1/10; containers for retaining a material to be analysed B01L3/50; containers for enzymology or microbiology C12M1/16; swab-sampler being part of enzymology or microbiology container C12M1/30)} - A61B 90/39: {Markers, e.g. radio-opaque or breast lesions markers} - A61B 10/0283: {with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe (A61B10/025, A61B10/0266 take precedence)} - A61B 2010/0208: {Biopsy devices with actuators, e.g. with triggered spring mechanisms} - A61B 2010/045: {Needles (pointed biopsy devices with vacuum aspiration A61B10/0283)} - A61B 2090/376: {using X-rays, e.g. fluoroscopy} - A61B 2090/3937: {Visible markers} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A biopsy device includes a body, a needle, a tissue sample holder and a sensor. The needle extends from the body. The tissue sample holder is in communication with the needle to receive one or more tissue samples within a sample chamber defined by the tissue sample holder. The tissue sample holder includes a receiving cavity. The sensor is configured to detect x-rays. The receiving cavity is sized and shaped to receive the sensor such that the sensor is removably positioned within the tissue sample holder. ## Claims ### Claim 1 A biopsy device with real-time imaging, comprising: (a) a body; (b) a needle extending from the body; (c) a tissue sample holder mounted to the body and in communication with the needle to receive one or more tissue samples; and (d) an x-ray sensor configured to be positioned proximate the tissue sample holder and adapted to receive an x-ray that has passed through the one or more received tissue samples. ### Claim 2 (depends on 1) The biopsy device of claim 1, wherein the tissue sample holder includes a plurality of sample chambers configured to receive and hold tissue samples. ### Claim 3 (depends on 1) The biopsy device of claim 1, wherein the tissue sample holder is configured to rotate relative to the body. ### Claim 4 (depends on 1) The biopsy device of claim 1, wherein the tissue sample holder includes a receiving cavity configured to receive the x-ray sensor and a plurality of sample chambers arranged around the receiving cavity, wherein the tissue sample holder is configured to rotate to orient the x-ray sensor relative to the plurality of sample chambers. ### Claim 5 (depends on 1) The biopsy device of claim 1, further comprising an imaging device, wherein the imaging device is configured to transmit x-rays, wherein the imaging device and the x-ray sensor are configured to cooperate to generate x-ray images. ### Claim 6 (depends on 1) The biopsy device of claim 1, further comprising a processor coupled to the x-ray sensor and adapted to process the received x-rays in real-time as the biopsy of the one or more tissue samples are taking place. ### Claim 7 (depends on 1) The biopsy device of claim 1, further comprising a processor coupled to the x-ray sensor and a control module that controls the biopsy of the one or more tissue samples, the processor controlling an x-ray source to transmit the x-rays through the tissue sample and processing an image from the x-rays received from the x-ray sensor in response to a signal from the control module indicating that a biopsy has been taken. ### Claim 8 (depends on 1) The biopsy device of claim 1, further comprising an imaging device, wherein the tissue sample holder includes a receiving cavity for receiving the x-ray sensor and a plurality of sample chambers oriented around the receiving cavity, wherein the imaging device and the x-ray sensor are configured to cooperate to generate x-ray image of each sample chamber of the plurality of sample chambers separately. ### Claim 9 (depends on 1) The biopsy device of claim 1, wherein the tissue sample holder includes a plurality of sample chambers oriented around a cavity, wherein the cavity is configured to receive the x-ray sensor therein to receive x-rays transmitted through the one or more sample chambers of the plurality of sample chambers. ### Claim 10 (depends on 1) The biopsy device of claim 1, wherein the sensor includes an electronic circuit, an imager, a fiber optic plate and a scintillator. ### Claim 11 A biopsy device comprising: (a) a body; (b) a needle extending distally from the body; (c) a tissue sample holder including one or more tissue chambers configured to store tissue samples therein; and (d) at least one sensor positioned within the tissue sample holder adjacent to a tissue chamber of the one or more tissue chambers, wherein the at least one sensor is operable to receive radiation from an imaging device, wherein the at least one sensor is configured to digitally transmit data in response to the radiation from the imaging device. ### Claim 12 (depends on 11) The biopsy device of claim 11, wherein the at least one sensor is securely fixed relative to the body such that the at least one sensor maintains a static orientation during rotation of the tissue sample holder relative to the body. ### Claim 13 (depends on 11) The biopsy device of claim 11, wherein the tissue sample holder includes a plurality of tissue chambers. ### Claim 14 (depends on 11) The biopsy device of claim 11, wherein the tissue sample holder includes a plurality of tissue chambers, wherein the at least one sensor includes a plurality of sensors with each sensor corresponding to each tissue chamber of the plurality of tissue chambers. ### Claim 15 (depends on 14) The biopsy device of claim 14, wherein the sensors are securely fixed relative to the tissue sample holder such that the sensors are configured to rotate during rotation of the tissue sample holder relative to the body. ### Claim 16 (depends on 15) The biopsy device of claim 15, wherein each sensor of the plurality of sensors is sized and shaped to be substantially equal to a dimensions of each corresponding sample chamber. ### Claim 17 A method of taking an image of a biopsied tissue sample from a biopsy device, the method comprising the steps of: (a) inserting a needle into a patient to severe and extract a tissue sample; (b) storing the tissue sample in a tissue sample holder; (c) inserting a digital sensor into the tissue sample holder such that the digital sensor is positioned adjacent to the tissue sample; (d) positioning an imaging device adjacent to the tissue sample holder such that a beam-transmitter of the imaging device is aligned towards the tissue sample and the digital sensor; and (e) activating the imaging device to transmit energy towards the tissue sample and digital sensor. ### Claim 18 (depends on 17) The method of claim 17, further comprising generating an image of the tissue sample. ### Claim 19 (depends on 17) The method of claim 17, further comprising generating an image of the tissue sample, further comprising displaying a graphical representation of the tissue sample. ### Claim 20 (depends on 17) The method of claim 17, further comprising generating an image of the tissue sample, further comprising displaying a graphical representation of the tissue sample, further comprising rotating the tissue sample holder to align a different tissue sample with the beam-transmitter.