# US 2019/0167191 A1 · Diagnostic Eye Goggle System > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2019/0167191 A1 - Document ID: US20190167191A1 - Status: Published application - Kind: A1 - Application number: 15/832,233 - Filed: 2017-12-05 - Published: 2019-06-06 - Earliest claimed: 2017-12-05 - Assignees: Renegade OptoPhysics LLC - Applicants: Renegade OptoPhysics LLC - Inventors: Michael A. Brewer; Shannon Rose Hinkley - Web page: https://patentgrep.com/patent/US20190167191A1 ## CPC - A61B 5/6803: {Head-worn items, e.g. helmets, masks, headphones or goggles} - A61B 3/1015: {for wavefront analysis} - A61B 3/113: for determining or recording eye movement - A61B 5/0075: {by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy (A61B5/0071 takes precedence)} - A61B 5/02438: {with portable devices, e.g. worn by the patient} - A61B 5/14555: {specially adapted for the eye fundus} - A61B 5/4842: {Monitoring progression or stage of a disease} - A61F 9/029: {Additional functions or features, e.g. protection for other parts of the face such as ears, nose or mouth; Screen wipers or cleaning devices} - A61B 3/1233: {for measuring blood flow, e.g. at the retina} - A61B 5/02416: {using photoplethysmograph signals, e.g. generated by infrared radiation (A61B5/14552 takes precedence)} - G02B 2027/0178: {Eyeglass type (eyeglass details G02C)} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS ## Abstract A diagnostic eye goggle system is described herein. The diagnostic eye goggle system includes goggles having a radiation source, a radiation sensor, optical elements, and a microcontroller for acquiring optical data from a user's eye including, but not limited to, wavefront data, spectral data, and frequency-shifted wavelength data. An external master database stores historical user data from previous users of the diagnostic eye goggle system. A transceiver disposed in the goggles provides a datalink between the acquired optical data and the external master database. A diagnostic software module cross-correlates the acquired optical data with the historical data to provide a diagnosis of a disease state of the user. The goggles further provide lens-correcting instructions or suggestions to a user or health care provider based on the acquired wavefront data. ## Claims ### Claim 1 A diagnostic eye goggle system to identify at least one of a disease state or a disease stage of a user and detect eye aberrations for corrective lensing, said eye goggles system comprising: goggles and an external master database having historical user data, said goggles having a front panel situated in front of the user's eyes when the goggles are worn about the user's head, said front panel comprising: one or more electromagnetic radiation sources disposed to emit radiation into one or more eyes of the user; one or more radiation sensors disposed to detect at least one of refraction, reflection, interference, intensity, frequency-shift, wavefront, or a spectrum of reflected radiation reflected from one or more structures in the user's eye; one or more optical elements disposed between the radiation source and the radiation sensor for manipulating at least one of the emitted radiation and the reflected radiation; a microcontroller disposed in communication with at least one of the electromagnetic radiation source, the radiation sensor, or the optical elements, said microcontroller coordinating the emission of radiation into the user's eye, and analyzing data received from the radiation sensors; and a transceiver disposed in communication with the microcontroller, said transceiver forming a datalink between the microcontroller and the external master database to permit the transmission of data therebetween, wherein a diagnostic software module can cross-correlate the analyzed data from the microcontroller with the historical user data in the master database to identify at least one of the disease state or the disease stage of the user. ### Claim 2 (depends on 1) The diagnostic eye goggle system of claim 1 wherein the microcontroller comprises a processor and memory, said memory storing three or more optical data acquisition modules, said modules having software executable instructions that when executed by the processor cause the processor to acquire three or more different types of optical data from the eye. ### Claim 3 (depends on 2) The diagnostic eye goggle system of claim 2 wherein a first optical data acquisition module when executed by the processor causes the processor to: command at least one of the radiation source and optical elements to emit one or more pulses of radiation onto the retina of the user's eye, wherein a wavefront of reflected radiation is detected by the sensor and transferred to the microcontroller for eye aberration analysis. ### Claim 4 (depends on 3) The disease detecting eye goggle system of claim 3 wherein a second optical data acquisition module when executed by the processor causes the processor to: command at least one of the radiation source and optical elements to emit one or more pulses of a continuous spectrum of radiation on one or more blood vessels or tissue structures in the user's eye, wherein a spectrum of the reflected radiation is detected by the sensor and transferred to the microcontroller for at least one of analyte or structure analysis of the eye. ### Claim 5 (depends on 4) The disease detecting eye goggle system of claim 4 wherein a third optical data acquisition module when executed by the processor causes the processor to: command at least one of the radiation source and optical elements to emit one or more specific wavelengths of radiation on one or blood vessels or tissue structures in the eye, wherein a frequency-shifted wavelength of reflected light is detected by the sensor and transferred to the microcontroller for at least one of analyte or structure analysis of the eye. ### Claim 6 (depends on 5) The diagnostic eye goggle system of claim 5 wherein a fourth optical data acquisition module when executed by the processor causes the processor to: command at least one of the radiation source and optical elements to emit one or more pulses of radiation at one or more target locations in the eye, wherein an angular degree of reflected radiation is detected by the sensor and transferred to the microcontroller to analyze a topography of the targeted locations. ### Claim 7 (depends on 6) The diagnostic eye goggle system of claim 6 wherein the microcontroller generates a mathematical map of the eye, said map having map data corresponding to an analyzed wavefront, an analyzed spectra of reflected radiation, and an analyzed frequency-shift of reflected radiation, wherein the mathematical map of the eye is transferred and stored in the master database, and the diagnostic software module cross-correlates the mathematical map of the eye with historical user's mathematical maps to identify a disease state of the user. ### Claim 8 (depends on 7) The diagnostic eye goggle system of claim 7 wherein the map data corresponding to the analyzed wavefront is comprised of Zernike Polynomials, and the map data corresponding to the analyzed spectra of reflected radiation comprises one or more spectral line fingerprints associated with one or more analyte spectral line fingerprints. ### Claim 9 (depends on 7) The diagnostic eye goggle system of claim 7 wherein the master database further receives and stores medical history data of the user that is linked to the user's mathematical map, wherein the diagnostic software module cross-correlates a present user's mathematical map with a historical user's mathematical map to identify a statistical match therebetween, and subsequently identify at least one of the disease state or disease stage of the present user based on the medical history of the matched historical user. ### Claim 10 (depends on 2) The diagnostic eye goggle system of claim 2 wherein the goggles further comprise read-write memory disposed in communication with the microcontroller, said read-write memory storing optical eye data acquired from two or more users. ### Claim 11 (depends on 10) The diagnostic eye goggle system of claim 10 wherein the read-write memory stores optical eye data acquired from two or more remote users when the datalink between the microcontroller and the external database is disconnected, wherein the transceiver transmits the optical eye data from the two or more remote users to the external master database when the datalink is restored. ### Claim 12 (depends on 11) The diagnostic eye goggle system of claim 11 wherein the read-write memory further stores historical user data, wherein the diagnostic software module cross-correlates the optical eye data acquired from the two or more remote users with the historical data stored in the read-write memory when the datalink between the microcontroller and the external master database is disconnected to identify at least one to of a disease state or disease stage of the user. ### Claim 13 (depends on 9) The diagnostic eye goggle system of claim 9 wherein the optical elements include actuating components to actively manipulate at least one of the emitted radiation or the reflected radiation. ### Claim 14 (depends on 10) The diagnostic eye goggle system of claim 10 wherein the three or more optical data acquisition modules when executed by the processor cause the processor to: actively direct the emitted radiation to a plurality of specific locations on the retina by actively adjusting one or more of the optical elements with the actuating components. ### Claim 15 (depends on 11) The diagnostic eye goggle system of claim 11 further comprising a camera disposed in the front panel and in communication with the microcontroller, said camera having an eye tracking software module for locating and tracking the pupil of the eye, wherein the emitted radiation is actively directed based, in part, on a current position of the user's pupil. ### Claim 16 (depends on 1) The diagnostic eye goggle system of claim 1 wherein the one or more electromagnetic radiation sources includes at least one of a light emitting diode (LED), a solid-state laser, an incandescent light, a fluorescent light, or a combination thereof to emit radiation in the range of 380 nanometers in wavelength to 2500 nanometers in wavelength; the one or more radiation sensors includes at least one of a charged-coupled device (CCD) sensor, a Hartmann-Shack wavefront sensor, or an array of photodiodes, or a combination thereof; and the one or more optical elements includes at least one of a slit, a pinhole, a collimator, a mirror, a beam-splitter, a lens, an x-y scanner, an x-y-z scanner, a prism, a reference arm, or a combination thereof. ### Claim 17 (depends on 1) The diagnostic eye goggle system of claim 1 wherein the diagnostic software module cross-correlates a wavefront of the user's eye with historical wavefront data to provide lens-correcting suggestions. ### Claim 18 (depends on 1) A method for identifying at least one of a disease state or a disease stage of a user with the diagnostic eye goggle system of claim 1, said method comprising: assembling the goggles about the user's head wherein the front panel is situated in front of the user's eyes; emitting a first set of radiation on the user's retina with the radiation source; detecting and collecting a wavefront of reflected radiation reflected from the user's retina with the sensor; emitting a second set of radiation on the user's retina with the radiation source; detecting and collecting a spectrum of reflected radiation reflected from the user's retina with the sensor; emitting a third set of radiation on the user's retina with the radiation source; detecting and collecting a wavelength of reflected radiation reflected from the user's retina with the sensor; generating, with the microcontroller, a mathematical map of the eye based on the wavefront, spectrum, and wavelength of the reflected radiation; transmitting and storing the mathematical map of the eye to a master database for identifying at least one of a disease state or disease stage of a future user of the goggles; and cross-correlating the mathematical map of the eye with historical user's mathematical maps to identify at least one of a disease state or a disease stage of the user. ### Claim 19 (depends on 18) The method of claim 18 further comprising: locating at least one of a tissue, tissue structure, or blood vessel prior to emitting at least one of the first set of radiation, the second set of radiation, or the third set of radiation; and transmitting and storing medical history data of the user to the master database to identify at least one of a disease state or disease stage of a future user. ### Claim 20 (depends on 18) The method of claim 18 further comprising: repeating the method of claim 18 at several time points for a user having a particular disease to track and store the changes of the mathematical map as a function of disease progression or regression.