# US 2019/0166877 A1 · Feed additive compositions

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- Number: US 2019/0166877 A1
- Document ID: US20190166877A1
- Status: Published application
- Kind: A1
- Application number: 16/139,621
- Filed: 2018-09-24
- Published: 2019-06-06
- Earliest claimed: 2017-12-06
- Assignees: NutriQuest, LLC
- Applicants: NutriQuest, LLC
- Inventors: Kim Friesen; Ran Song; Robert Musser
- Web page: https://patentgrep.com/patent/US20190166877A1

## CPC

- A23K 20/158: Fatty acids; Fats; Products containing oils or fats
- A23K 10/30: from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms (obtained by microbiological or biochemical processes, e.g. using yeasts or enzymes, A23K10/10)
- A23K 20/189: Enzymes
- A23K 50/00: Feeding-stuffs specially adapted for particular animals
- A23K 50/10: for ruminants
- A23K 50/20: for horses
- A23K 50/30: for swines
- A23K 50/80: for aquatic animals, e.g. fish, crustaceans or molluscs
- A61K 31/00: Medicinal preparations containing organic active ingredients
- A23K: FODDER
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

The present disclosure provides feed composition comprising at least one cyclopropenoid fatty acids or at least one conjugated linoleic acid and at least one cyclopropenoid fatty acids with normal or basal feed. After administration of one of the feed compositions, improved health aspects, reduced health issues, reduced mortality, increased carcass gain and repartitioning nutrients to muscles, and controlled carcass iodine value in non-human animals as compared to a control group not fed with the feed composition.

## Claims

### Claim 1

A feed composition for non-human animals comprising at least one conjugated linoleic acid (CLA) and at least one cyclopropenoid fatty acid (CPFAs).

### Claim 2 (depends on 1)

The feed composition of claim 1, wherein the feed composition further comprises a normal basal feed.

### Claim 3 (depends on 1)

The feed composition of claim 1, wherein the composition comprises between 0.56 lbs/ton to about 5.6 lbs/ton of at least one conjugated linoleic acid.

### Claim 4 (depends on 3)

The feed composition of claim 3, wherein the composition comprises between 2.24 lbs/ton to about 4.48 lbs/ton of the at least one conjugated linoleic acid.

### Claim 5 (depends on 1)

The feed composition of claim 1, wherein the at least one conjugated linoleic acid (CLA) comprises cis-9, trans-11-octadecadienoic acid, trans-10, cis-12-octadecadienoic acid, or combinations thereof.

### Claim 6 (depends on 1)

The feed composition of claim 1, wherein the at least one conjugated linoleic acid is a synthetic substance, derived from a natural substance, derived from algae, derived from bacterial fermentation, or combinations thereof.

### Claim 7 (depends on 1)

The feed composition of claim 1, wherein the at least one conjugated linoleic acid is a pure liquid, a suitable acceptable salt of the at least one conjugated linoleic acid, an oil comprising the at least one conjugated linoleic acid, or combinations thereof.

### Claim 8 (depends on 7)

The feed composition of claim 7, wherein the oil comprising the at least one conjugated linoleic acid is from about 20 weight % to about 80 weight % of the at least one conjugated linoleic acid.

### Claim 9 (depends on 1)

The feed composition of claim 1, wherein the composition comprises between 30 gram/ton to about 306 gram/ton of the at least one cyclopropenoid fatty acid.

### Claim 10 (depends on 9)

The feed composition of claim 9, wherein the composition comprises between 90 gram/ton to about 245 gram/ton of the at least one cyclopropenoid fatty acid.

### Claim 11 (depends on 1)

The feed composition of claim 1, wherein the at least one cyclopropenoid fatty acid comprises sterculic acid, malvalic acid, dihydrosterculic acid, or combinations thereof.

### Claim 12 (depends on 1)

The feed composition of claim 1, wherein the at least one cyclopropenoid fatty acid is a synthetic substance, derived from a natural substance, derived from bacterial fermentation, derived from algae, or combinations thereof.

### Claim 13 (depends on 1)

The feed composition of claim 1, wherein the at least one cyclopropenoid fatty acid is a liquid, a suitable acceptable salt of the at least one cyclopropenoid fatty acid, an oil comprising the at least one cyclopropenoid fatty acid, or combinations thereof.

### Claim 14 (depends on 1)

The feed composition of claim 1, wherein the oil comprising the at least one cyclopropenoic fatty acid is from 10% weight to about 60% weight of the at least one conjugated cyclopropenoid fatty acid.

### Claim 15 (depends on 1)

A method for improving growth aspects in a non-human animal, the method comprising the step of administering the feed composition of claim 1 to a non-human animal, wherein after administration to the non-human animal, the non-human animal shows improved growth aspects not exhibited by feed compositions comprising conjugated linoleic acid (CLA) alone.

### Claim 16 (depends on 15)

The method of claim 15, wherein the improved growth aspects are measured by an increase in the average daily weight gain (ADG), improvement in feed conversion, reduced health issues, reduced mortality, or combinations thereof.

### Claim 17 (depends on 15)

The method of claim 15, wherein the average daily intake of the at least one conjugated linoleic acid ranges from about 1.0 g/day to about 10.0 g/day for the non-human animal.

### Claim 18 (depends on 15)

The method of claim 15, wherein the average daily intake of the at least one cyclopropenoid fatty acid ranges from about 0.1 g/day to about 1.0 g/day for the non-human animal.

### Claim 19 (depends on 15)

The method of claim 15, wherein the feed composition is administered to the non-human animal at least once per day.

### Claim 20 (depends on 15)

The method of claim 15, wherein the non-human animal is selected from a group comprising pigs, cattle, poultry, alpaca, bison, camel, donkey, goat, horse, llama, mule, rabbit, sheep, goat, deer, aquaculture fish, aquaculture crustaceans, aquaculture mollusks, aquaculture echinoderms, or combinations thereof.

### Claim 21 (depends on 1)

A method for increasing carcass gain and repartitioning nutrients to muscles (nitrogen retention) in a non-human animal, the method comprising the step of administering the feed composition of claim 1 to the non-human animal, wherein after administration to the non-human animal, the non-human animal shows increased carcass gain and repartitioned nutrients to muscles (nitrogen retention) not exhibited by feed compositions using conjugated linoleic acid (CLA) alone.

### Claim 22 (depends on 21)

The method of claim 21, wherein increased carcass gain and repartitioning nutrients to muscles (nitrogen retention) are measured by heavier hot carcass weight, greater carcass weight gain than total weight gain, increase loin depth, reduced back fat, increased carcass yield, increased lean percentage, or combinations thereof.

### Claim 23 (depends on 21)

The method of claim 21, wherein the average daily intake of the at least one conjugated linoleic acid ranges from about 1.0 g/day to about 10.0 g/day for the non-human animal.

### Claim 24 (depends on 21)

The method of claim 21, wherein the average daily intake of the at least one cyclopropenoid fatty acid ranges from about 0.1 g/day to about 1.0 g/day for the non-human animal.

### Claim 25 (depends on 21)

The method of claim 21, wherein the feed composition is administered to the non-human animal at least once per day.

### Claim 26 (depends on 21)

The method of claim 21, wherein the feed composition is administered at least once per day.

### Claim 27 (depends on 21)

The method of claim 21, wherein the non-human animal is selected from a group comprising pigs, cattle, poultry, alpaca, bison, camel, donkey, goat, horse, llama, mule, rabbit, sheep, goat, deer, aquaculture fish, aquaculture crustaceans, aquaculture mollusks, aquaculture echinoderms, or combinations thereof.

### Claim 28 (depends on 1)

A method for controlling carcass iodine value (IV) in a non-human animal, the method comprising the step of administering the feed composition of claim 1 to the non-human animal, wherein after administration to the non-human animal, the non-human animal shows a decrease in the carcass iodine value not exhibited by feed compositions using conjugated linoleic acid (CLA) alone.

### Claim 29 (depends on 28)

The method of claim 28, where iodine value is decreased 1 point for each 40 grams to 70 grams of a composition containing 7.4% of the at least one CPFA and 92.6% of the at least one CLA.

### Claim 30 (depends on 28)

The method of claim 28, wherein the controlled iodine value is measured by a decrease in the carcass iodine value, increasing saturated fatty acids, reducing mono- and polyunsaturated acid in the fat, decreasing delta-9 desaturase activity, reduction in carcass unsaturated fat content, increased melting point of the carcass, improved carcass hardness, jowl firmness, backfat firmness, stick to belly fat, or combinations thereof.

### Claim 31 (depends on 28)

The method of claim 28, wherein the average daily intake of the at least one conjugated linoleic acid ranges from about 1.0 g/day to about 10.0 g/day.

### Claim 32 (depends on 28)

The method of claim 28, wherein the average daily intake of the at least one cyclopropenoid fatty acid ranges from about 0.1 g/day to about 1.0 g/day for the non-human animal.

### Claim 33 (depends on 28)

The method of claim 28, wherein the feed composition is administered at least once per day for the non-human animal.

### Claim 34 (depends on 28)

The method of claim 28, wherein the non-human animal is selected from a group comprising pigs, cattle, poultry, alpaca, bison, camel, donkey, goat, horse, llama, mule, rabbit, sheep, goat, deer, aquaculture fish, aquaculture crustaceans, aquaculture mollusks, aquaculture echinoderms, or combinations thereof.

### Claim 35 (depends on 28)

A method for claim 28, wherein the iodine value potential (IVP) of the feed composition increases 2 to 10 points and the iodine value of the non-human animal is lowered after administration.
