# US 2019/0166843 A1 · Pesticidal Active Mixtures Comprising Isoxazoline Compounds I > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2019/0166843 A1 - Document ID: US20190166843A1 - Status: Published application - Kind: A1 - Application number: 16/270,694 - Filed: 2019-02-08 - Published: 2019-06-06 - Earliest claimed: 2008-07-09 - Assignees: BASF SE - Applicants: BASF SE - Inventors: Karsten KOERBER; Florian KAISER; Juergen LANGEWALD - Web page: https://patentgrep.com/patent/US20190166843A1 ## CPC - A01N 43/88: six-membered rings with three ring hetero atoms - A01N 43/40: six-membered rings - A01N 43/50: 1,3-Diazoles; Hydrogenated 1,3-diazoles - A01N 43/80: five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2 - A01N 43/90: having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system - A01N 53/00: Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof - A61K 31/277: having a ring, e.g. verapamil - A61K 31/42: Oxazoles - A61K 31/4427: containing further heterocyclic ring systems - A61K 31/4439: containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole (nicotine A61K31/465) - A61K 31/455: Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides - A61K 31/5395: having two or more nitrogen atoms in the same ring, e.g. oxadiazines - A61K 31/7048: having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin {, digitoxin or digoxin} - A61P 33/00: Antiparasitic agents - A61P 33/14: Ectoparasiticides, e.g. scabicides - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS ## Abstract The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one isoaxazoline compound I of the formula (I) wherein R1, R2, R3, R4, R5 and A are defined in the description; and 2) at least one active compound II selected from a group A comprising acteylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acteylcholine receptor agonists/antagonists, chloride channel activators, juvenile hormone mimics, compounds affecting the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, inhibitors of the MET, voltage-dependent sodium channel blockers, inhibitors of the lipid synthesis and other compounds as defined in the description, in synergistically effective amounts. The invention relates further to methods and use of these mixtures for combating insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant propagation material as like seeds. ## Claims ### Claim 1 A pesticidal mixture comprising 1) at least one isoxazoline compound I of formula I: or a salt thereof, and 2) at least one active compound II selected from selected from the group consisting of abamectin, emamectin benzoate, lepimectin and milbemectin ### Claim 2 (depends on 1) The mixture according to claim 1, wherein compound I is the compound of formula: or a salt thereof. ### Claim 3 (depends on 1) The mixture according to claim 1, wherein compound I is the compound of formula: or a salt thereof. ### Claim 4 (depends on 1) The mixture according to claim 1, wherein the active compound I and the active compound II are present in a weight ratio of 20:1 to 1:50. ### Claim 5 (depends on 4) The mixture according to claim 4, wherein the active compound I and the active compound II are present in a weight ratio of 5:1 to 1:20. ### Claim 6 (depends on 1) The mixture according to claim 1, wherein at least one active compound II is abamectin. ### Claim 7 (depends on 1) The mixture according to claim 1, wherein at least one active compound II is emamectin benzoate. ### Claim 8 (depends on 1) The mixture of claim 1, wherein at least one active compound II is lepimectin. ### Claim 9 (depends on 1) The mixture of claim 1, wherein at least one active compound II is milbemectin. ### Claim 10 (depends on 1) The mixture of claim 1, comprising one compound I. ### Claim 11 (depends on 10) The mixture of claim 10, wherein the compound I is compound C.I.240. ### Claim 12 (depends on 10) The mixture of claim 10, wherein the compound I is compound C.I.456. ### Claim 13 (depends on 10) The mixture of claim 10, comprising one compound II. ### Claim 14 (depends on 1) A method for protecting plants from attack or infestation by insects, acarids or nematodes comprising contacting the plant, or the soil or water in which the plant is growing, with a mixture according to claim 1 in pesticidally effective amounts. ### Claim 15 (depends on 1) A method for controlling insects, arachnids or nematodes comprising contacting an insect, acarid or nematode or their food supply, habitat, breeding grounds or their locus with a mixture according to claim 1 in pesticidally effective amounts. ### Claim 16 (depends on 14) The method as claimed in claim 14, wherein the mixture is applied in an amount of from 5 g/ha to 2000 g/ha. ### Claim 17 (depends on 1) A method for protection of plant propagation material comprising contacting the plant propagation material with a mixture of claim 1 in pesticidally effective amounts. ### Claim 18 (depends on 17) A method according to claim 17 wherein the mixture is applied in an amount of from 0.1 g to 10 kg per 100 kg of plant propagation material. ### Claim 19 (depends on 17) A method as claimed in claim 17, wherein the plant propagation material is/are seed(s). ### Claim 20 (depends on 19) The method of claim 19, wherein the mixture is applied in an amount of from 0.1 g to 10 kg per 100 kg of seeds. ### Claim 21 (depends on 1) A method for protecting animals against infestation or infection by parasites which comprises administering to the animals a parasitically effective amount of a mixture according to claim 1 to the animal in need thereof. ### Claim 22 (depends on 1) A method for treating animals infested or infected by parasites which comprises administering to the animals a parasitically effective amount of a mixture according claim 1 to the animal in need thereof. ### Claim 23 A method for controlling insects, arachnids or nematodes comprising contacting an insect, acarid or nematode or their food supply, habitat, breeding grounds or their locus with compound C.I.240 and/or compound C.I.456 or a salt thereof, and at least one active compound II selected from selected from the group consisting of abamectin, emamectin benzoate, lepimectin and milbemectin; wherein compound C.I.240 and/or compound C.I.456 and compound II are applied simultaneously, that is jointly or separately, or in succession. ### Claim 24 (depends on 1) A pesticidal or parasiticidal composition, comprising a liquid or solid carrier and a mixture according to claim 1.