# US 2019/0166830 A1 · Methods and compositions for killing of insect pest eggs > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2019/0166830 A1 - Document ID: US20190166830A1 - Status: Published application - Kind: A1 - Application number: 16/321,126 - Filed: 2017-08-02 - Published: 2019-06-06 - Earliest claimed: 2016-08-05 - Assignees: North Carolina State University - Applicants: North Carolina State University - Inventors: Richard Michael Roe - Web page: https://patentgrep.com/patent/US20190166830A1 ## CPC - A01N 35/02: containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS ## Abstract The invention is directed to ovicidal compositions comprising at least 2-undecanone and/or 2-tridecanone, and methods for the use of the compositions for the killing of insect pest eggs. ## Claims ### Claim 1 A method of killing insect eggs, comprising contacting the insect eggs with an effective amount of a composition comprising 2-undecanone and/or 2-tridecanone, thereby killing the insect eggs. ### Claim 2 (depends on 1) The method of claim 1, wherein the insect eggs are lice eggs. ### Claim 3 A method of killing lice eggs on a subject infested with lice eggs or suspected of being infested with lice eggs, comprising applying to the subject an effective amount of a composition comprising 2-undecanone and/or 2-tridecanone, thereby killing the lice eggs on the subject. ### Claim 4 A method of reducing the risk of infestation or re-infestation of a subject by lice, comprising applying to the subject an effective amount of a composition comprising 2-undecanone and/or 2-tridecanone, thereby killing the lice eggs on the subject. ### Claim 5 (depends on 1) The method of claim 1, wherein the composition comprises about 0.01% to about 30% of 2-undecanone and/or about 0.01% to about 30% of 2-tridecanone. ### Claim 6 (depends on 1) The method of claim 1, wherein the composition further comprises a solid carrier, a liquid carrier, or a gaseous carrier. ### Claim 7 (depends on 6) The method of claim 6, wherein the solid carrier is a powder or granules of cellulose, clays, talc, ceramics, and/or other inorganic minerals. ### Claim 8 (depends on 1) The method of claim 1, wherein the composition further comprises diatomaceous earth. ### Claim 9 (depends on 8) The method of claim 8, wherein the composition comprises about 1% to about 99.99% diatomaceous earth. ### Claim 10 (depends on 6) The method of claim 6, wherein the liquid carrier is water, a surfactant, an oil, an organic solvent, and/or any combination thereof. ### Claim 11 (depends on 10) The method of claim 10, wherein the surfactant is an alkyl sulfate, alkylsulfonate, alkylarylsulfonate, alkyl aryl ether, polyoxyethylenealkyl aryl ether, polyethylene glycol ether, polyhydric alcohol ether, sugar alcohol derivative, or any combination thereof. ### Claim 12 (depends on 10) The method of claim 10, wherein the organic solvent is ethanol and/or methanol. ### Claim 13 (depends on 6) The method of claim 6, wherein the gaseous carrier is air, carbon dioxide, and/or nitrogen. ### Claim 14 (depends on 1) The method of claim 1, wherein the composition is in the form of a powder, liquid, aerosol, gel, foam, lotion, or ointment. ### Claim 15 (depends on 1) The method of claim 1, wherein the killing occurs in at least about 1 second to about 10 seconds following the contacting of the insect eggs and/or lice eggs with the effective amount of the composition or after applying to the subject the effective amount of the composition, resulting in the killing of about 45% to about 100% of the insect eggs and/or lice eggs. ### Claim 16 (depends on 1) The method of claim 1, wherein the contacting comprises contacting a site of lice infestation on a subject with a dry shampoo, liquid shampoo, conditioner, creme rinse, mousse, foam, lotion, ointment, and/or aerosol comprising the composition. ### Claim 17 (depends on 3) The method of claim 3, wherein the composition is applied to the subject in the form of a dry shampoo, liquid shampoo, conditioner, creme rinse, mousse, foam, lotion, ointment, and/or aerosol that comprises the composition. ### Claim 18 (depends on 1) The method of claim 1, wherein the contacting comprises: covering a site of infestation on a subject having or being suspected of having lice eggs with a cap, wherein the cap comprises an inner side and an outer side, and the inner side is in contact with the site of infestation on the subject and comprises the composition; and massaging the cap while the cap is on the site of infestation, thereby massaging the composition into the subject's hair and scalp. ### Claim 19 (depends on 3) The method of claim 3, wherein the applying comprises: covering a site of infestation on a subject having or being suspected of having lice eggs with a cap, wherein the cap comprises an inner side and an outer side, and the inner side is in contact with the site of infestation on the subject and comprises the composition; and massaging the cap while the cap is on the site of infestation, thereby massaging the composition into the subject's hair and scalp. ### Claim 20 (depends on 3) The method of claim 3, wherein the composition that is applied to the subject or contacted with the eggs is therapeutically effective for at least about six hours to about five days.