# US 2019/0166829 A1 · Moisturizing liquid composition with cationic biocide

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- Number: US 2019/0166829 A1
- Document ID: US20190166829A1
- Status: Published application
- Kind: A1
- Application number: 15/829,363
- Filed: 2017-12-01
- Published: 2019-06-06
- Earliest claimed: 2017-12-01
- Applicants: Henkel IP & Holding GmbH
- Inventors: Jessica Lawshe; Janice L. Fuls; Gregory Cole
- Web page: https://patentgrep.com/patent/US20190166829A1

## CPC

- A01N 33/12: Quaternary ammonium compounds
- A01N 39/00: Biocides, pest repellants or attractants, or plant growth regulators containing aryloxy- or arylthio-aliphatic or cycloaliphatic compounds, containing the group [IMAGE cpc-sch-A01N-0940.gif] or [IMAGE cpc-sch-A01N-0941.gif], e.g. phenoxyethylamine, phenylthio-acetonitrile, phenoxyacetone
- A61K 8/27: Zinc; Compounds thereof
- A61K 8/345: {containing more than one hydroxy group}
- A61K 8/362: Polycarboxylic acids
- A61K 8/40: containing nitrogen (quinones containing nitrogen A61K8/355)
- A61K 8/416: {Quaternary ammonium compounds (A61K8/35 takes precedence)}
- A61K 8/42: Amides
- A61Q 17/005: {Antimicrobial preparations}
- A61Q 19/10: Washing or bathing preparations
- A61Q 19/007: {Preparations for dry skin}
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A liquid cleaning composition including: at least 80 wt. % liquid solvent; a cationic quaternary amine biocide; and a non-cationic moisturizing agent, wherein the composition reduces bacteria by at least 2.0 log 10 when assessed using ASTM E1174 and reduces drying of the stratum corneum compared with a water control between 30 and 180 minutes after application.

## Claims

### Claim 1

A liquid cleaning composition, the composition comprising:
at least 80 wt. % liquid solvent;
a cationic quaternary amine biocide; and
a non-cationic moisturizing agent,
wherein the composition reduces bacteria by at least 2.0 log 10 when assessed using ASTM E1174 and reduces drying of the stratum corneum compared with a water control between 30 and 180 minutes after application.

### Claim 2 (depends on 1)

The composition of claim 1, further comprising an ionic zinc compound, wherein the zinc compound comprises 0.01 wt. % to 0.5 wt. 5 of the composition.

### Claim 3 (depends on 1)

The composition of claim 1, further comprising a second cationic quaternary amine biocide, wherein the second cationic quaternary amine biocide comprises 0.5 wt. % to 5 wt. % of the composition.

### Claim 4 (depends on 1)

The composition of claim 1, wherein the composition is substantially free of low molecular weight mono-alcohols.

### Claim 5 (depends on 1)

The composition of claim 1, wherein the liquid solvent is water.

### Claim 6 (depends on 1)

The composition of claim 1, wherein the reduction in drying of the stratum corneum is assessed with a lower leg controlled application test (LCAT).

### Claim 7 (depends on 1)

The composition of claim 1, wherein the cationic quaternary amine biocide is benzalkonium chloride (BAC).

### Claim 8 (depends on 1)

The composition of claim 1, further comprising two non-ionic surfactants.

### Claim 9 (depends on 1)

The composition of claim 1, further comprising 0.002 wt. % to 5 wt. % of an unmodified polyglycol of 6 to 12 repeat units.

### Claim 10

A liquid cleaning composition, the composition comprising:
at least 80 wt. % water;
a first cationic quaternary amine biocide;
a second cationic quaternary amine biocide; and
an unmodified polyglycol,
wherein the composition reduces bacteria by at least 2.0 log 10 when assessed using ASTM E1174 and reduces drying of the stratum corneum compared with a water control between 30 and 180 minutes after application as assessed with a lower leg controlled application test (LCAT).

### Claim 11 (depends on 10)

The composition of claim 10, further comprising an ionic zinc compound, wherein the zinc compound comprises 0.01 wt. % to 0.5 wt. % of the composition.

### Claim 12 (depends on 10)

The composition of claim 10, wherein the first cationic quaternary amine biocide is benzalkonium chloride (BAC) and the second cationic quaternary amine biocide is a cetrimonium salt.

### Claim 13 (depends on 10)

The composition of claim 10, further comprising a non-ionic surfactant, wherein the non-ionic surfactant comprises 0.03 wt. % to 6 wt. % of the composition.

### Claim 14

A liquid cleaning composition, the composition comprising:
at least 80 wt. % water;
0.06 wt. % to 1 wt. % of a cationic biocide;
0.7 wt. % to 3 wt. % glycerin;
0.01 wt. % to 5 wt. % of a polycarboxylic acid and/or salt thereof; and
0.01 wt. % to 1 wt. % myristamidopropylamine oxide.

### Claim 15 (depends on 14)

The composition of claim 14, wherein the cationic biocide comprises benzethoium chloride (BZC).

### Claim 16 (depends on 14)

The composition of claim 14, wherein the polycarboxyllic acid and/or salt thereof is comprises three carboxyl groups per molecule.

### Claim 17 (depends on 14)

The composition of claim 14, wherein the polycarboxylic acid and/or salt comprises an acid selected from the group consisting of: citric acid, a citrate salt, ethylenediaminetetraacetic acid (EDTA), an EDTA salt, oxalic acid, an oxalate salt, and mixtures thereof.

### Claim 18 (depends on 14)

The composition of claim 14, wherein the composition is at least 90 wt. % water.

### Claim 19 (depends on 14)

The composition of claim 14, further comprising a non-ionic surfactant.

### Claim 20 (depends on 14)

The composition of claim 14, further comprising an unmodified polyethylene glycol of 5 to 18 C2H4 repeat units linked by ether bonds and also comprising a non-ionic surfactant.