Proxy-less wide area network acceleration

A system comprising:

• a processor;
• a data bus coupled to the processor;
• and
• a non-transitory, computer-readable storage medium embodying computer program code, the non-transitory, computer-readable storage medium being coupled to the data bus, the computer program code interacting with a plurality of computer operations and comprising instructions executable by the processor and configured for, responsive to receiving at an acceleration device a stream of one or more datagrams from a sending endpoint device within a first local area network of the acceleration device, the stream for transmission to a receiving endpoint device within a second local area network coupled to the first local area network by a wide area network:
• communicating by the acceleration device to the sending endpoint device a respective acknowledgement to each of the one or more datagrams;
• and
• transmitting by the acceleration device the one or more datagrams via multiple communication links of the wide area network to a second acceleration device within the second local area network and coupled to the receiving endpoint device.