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US 2019/0164736 A1Published application
Devices and methods for mai ionization
AssigneeBoard of Supervisors of Louisiana State University and Agricultural and Mechanic
InventorsKermit King Murray, Bijay Kumar Banstola
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Abstract
Mass spectrometry systems and methods including ionization devices are provided. The ionization device includes either a gas pulse valve or a piezoelectric striker. The ionization device is configured to direct force to the back of a substrate, where an analyte of interest is deposited on the front of the substrate. The impact ionizes the analyte and the ions are directed into a mass spectrometer for analysis.
Claims18
A mass spectrometer system comprising:
- a sample mount configured to hold a sample substrate, wherein the sample substrate has an opposing front side and a back side, wherein a sample is on the front side of the sample substrate;
- an ionization device configured to direct a force at the back side of a sample substrate to propagate a shockwave, wherein the ionization device is at a first distance adjacent the sample mount;
- and
- a mass spectrometer having an inlet, wherein the sample mount is positioned a second distance from the inlet.
1 more element
A method for mass spectrometer ionization comprising:
- directing a force at a back side of a sample substrate, wherein a sample is disposed on a front side of the sample substrate opposite of where the force is directed, wherein the sample includes at least one analyte;
- and
- forming ions of one or more of the analytes upon impact of the force on the back side of the sample substrate.
Dependencies are inferred from the claim text.