Anti-t. cruzi antibodies and methods of use
AssigneeAbbott Laboratories
InventorsDavid J. Hawksworth, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Susan E. Brophy, Dinesh O. Shah, Joan D. Tyner, Robert N. Ziemann
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Abstract
The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
Claims20
-42. (canceled)
An immunodiagnostic reagent comprising one or more antibodies that specifically bind to a T. cruzi FRA polypeptide, wherein the T. cruzi FRA polypeptide comprises an amino acid sequence of SEQ ID NO:
- 8, and wherein each of the one or more antibodies comprises a variable light chain region (VL) comprising an amino acid sequence of SEQ ID NO:
- 26 and a variable heavy chain region (VH) comprising an amino acid sequence of SEQ ID NO:
- 28.
An antibody that specifically binds to a T. cruzi FRA polypeptide comprising the amino acid sequence of SEQ ID NO:
- 8, wherein the antibody comprises a variable light chain region (VL) comprising an amino acid sequence of SEQ ID NO:
- 26 and a variable heavy chain region (VH) comprising an amino acid sequence of SEQ ID NO:
- 28.
A cell line deposited with the ATCC under accession number PTA-8142.
Dependencies are inferred from the claim text.