Rna determinants for distinguishing between bacterial and viral infections
AssigneeMeMed Diagnostics Ltd.
InventorsKfir OVED, Eran EDEN, Olga BOICO, Gali KRONENFELD, Roy NAVON, Assaf COHEN-DOTAN, Einav SIMON
Life of this patent
Estimating the term…
Abstract
Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.
Claims40
A method of determining an infection type in a subject comprising measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.
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11-12. (canceled)
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19-24. (canceled)
A method of determining an infection type in a subject comprising measuring the amount of at least one RNA as set forth in Table 3 or Table 4, in a sample derived from the subject, wherein no more than 20 RNAs are measured, wherein said amount of at least one RNA is indicative of the infection type.
30-31. (canceled)
A method of determining an infection type in a subject comprising measuring the amount of at least one RNA as set forth in Table 5 or Table 6A, in a sample derived from the subject, wherein no more than 5 RNAs are measured, wherein said amount of at least one RNA is indicative of the infection type.
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A kit for diagnosing an infection type comprising at least two RNA detection reagents, wherein the first of said at least two RNA detection reagents specifically detects a first RNA which is set forth in Table 3 or Table 4, and a second of said at least two RNA detection reagents specifically detects a second RNA which is set forth in any one of Tables 1-6A or Tables 15A-B, wherein the kit comprises detection reagents that specifically detect no more than 20 RNAs.
A kit for diagnosing an infection type comprising at least two determinant detection reagents, wherein the first of said at least two determinant detection reagents specifically detects a first determinant which is set forth in any one of Tables 1-6A or Tables 15A-B and a second of said at least two determinant detection reagents specifically detects a second determinant which is set forth in any one of Tables 1-6A or Tables 15A-B, wherein the kit comprises detection reagents that specifically detect no more than 5 determinants.
55-58. (canceled)
A method of distinguishing between an infectious and non-infectious subject comprising measuring the amount of a determinant which is set forth in Table 16E in a sample derived from the subject, wherein said amount is indicative whether the subject is infectious or non-infectious.
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Dependencies are inferred from the claim text.