Method for predicting prognosis of breast cancer patients by using gene deletions

Abstract

The present invention relates to a method for predicting the prognosis of breast cancer patients by using gene deletions and, more particularly, to: a method for detecting a marker for the prognosis of triple negative breast cancer patients in order to provide information necessary for the breast cancer prognosis diagnosis, comprising the steps of obtaining a sample of a subject, extracting genomic DNA from the sample, examining deletions of genes in the extracted genomic DNA, and determining that a subject, in which gene deletions in genomic DNA are confirmed, has a poor prognosis for breast cancer; and a composition for predicting the prognosis of breast cancer patients, containing a preparation enabling the examination of gene deletions and a kit comprising the same as an active ingredient. As investigated by the present inventors, deletions of a plurality of specific genes in triple negative breast cancer tissues are closely correlated with the prognosis of breast cancer patients, and thus the method and composition, of the present invention, which are for detecting deletions of relevant genes as a marker, are useful in providing information for determining the prognosis of breast cancer, particularly triple negative breast cancer for which efficient biomarkers are absent.

Dependencies are inferred from the claim text.