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US 2019/0161755 A1Published application
Compositions and methods for inhibiting factor d
AssigneeVitrisa Therapeutics, Inc.
InventorsCarl Erickson, Christopher P. Rusconi, Kevin G. McLure
Life of this patent
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Abstract
The application discloses methods and compositions for the inhibition of the alternative complement pathway. The methods and compositions involve the use of aptamers for inhibiting complement Factor D. The application further provides anti-Factor D aptamers for the treatment of dry age-related macular degeneration, geographic atrophy, wet age-related macular degeneration or Stargardt disease.
Claims25
-18. (canceled)
A method comprising:
- administering to a subject in need thereof a therapeutically effective amount of an aptamer that selectively blocks a catalytic cleft of complement Factor D.
-24. (canceled)
-29. (canceled)
-66. (canceled)
Dependencies are inferred from the claim text.