Methods for using fxr agonists
AssigneeNovartis AG
InventorsMichael Badman, Clifford Brass, Bryan Laffitte
Life of this patent
Estimating the term…
Abstract
The invention provides methods for modulating the activity of farnesoid X receptors (FXRs) using specific doses of tropifexor, in particular for treating or preventing liver diseases.
Claims10
A method for treating or preventing a condition mediated by Farnesoid X receptor (FXR), e.g. liver disease or disorder, the method comprising the step of administering n tropifexor to a patient in need thereof at a dose in a range of about 140 μg to about 250 μg.
A pharmaceutical unit dosage form composition comprising about 140 μg, about 1500 μg, about 160 μg, about 170 μg, about 180 μg, about 190 μg, about 200 μg about 210 μg, about 220 μg, about 230 μg, about 240 μg or about 250 μg of tropifexor suitable for oral administration up to a maximum total dose of about 500 μg per day.
Dependencies are inferred from the claim text.