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US 2019/0161470 A1Published application
Antifungal Compound Process
AssigneeMycovia Pharmaceuticals, Inc.
InventorsWilliam J. HOEKSTRA, Christopher M. YATES
Life of this patent
Estimating the term…
Abstract
The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
Claims9
1-14. (canceled)
A process to prepare compound 1 or 1a, or a mixture thereof:
- comprising forming a ketone of a compound of formula 3,
- to provide compound of formula 15,
- wherein R is halo or
16-23. (canceled)
28-29. (canceled)
A compound of formula I:
- wherein R″ is —OH or —OTMS;
- R′″ is —CN or —CH2NH2;
- Y is
- alternatively R″ and R′″ may be taken together to form a carbonyl.
1 more element
Dependencies are inferred from the claim text.