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US 2019/0161453 A1Published application
Oxoalkyl-substituted phenyltriazole derivatives and uses thereof
AssigneeBayer Pharma Aktiengesellschaft
InventorsCarsten SCHMECK, Anna ENGELEN, Peter KOLKHOF, Klemens LUSTIG, Elisabeth POOK, Pierre WASNAIRE
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Abstract
The present invention relates to novel Oxoalkyl-substituted 1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
Claims12
A compound of general formula (I-A) or a compound of general formula (I-B)
- in which
- R1 represents a group of the formula
- in which
- #1 represents the point of attachment to the nitrogen atom,
- and
- Ar represents a phenyl group optionally substituted with one or two groups selected from a fluoro atom, a chloro atom, cyano, methyl, fluoromethyl, difluoromethyl, trifluoromethyl, ethyl, methoxy, difluoromethoxy and trifluoromethoxy,
- or a pharmaceutically acceptable salt, hydrate and/or solvate thereof.
4 more elements
Dependencies are inferred from the claim text.