US 2019/0161432 A1Published application

4-alkoxy-3-(trifluoromethyl)benzyl alcohol production method

AssigneeMitsubishi Tanabe Pharma Corporation

InventorsMakoto KAWANO, Takashi NAKA, Mitsuharu NAKAMURA, Hisao TAKAYANAGI

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Abstract

The present invention relates to a production method of 4-alkoxy-3-trifluoromethylbenzyl alcohol at a high conversion ratio, which can strictly suppress production of a byproduct by using DIBAL as a reducing agent.

Claims10

Dependent claims

A production method of a compound represented by the following formula (II), the method comprising reducing a compound represented by the following formula (I) by using diisobutylaluminum hydride:

wherein R is alkyl having 1 to 10 carbon atoms.

Dependencies are inferred from the claim text.

Facts

Application: 16/321,299Filed 28 Jul 2017
Priority: JP 2016-14990529 Jul 2016
Published: 30 May 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

C07C 213/02
Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same…: by…
C07C 213/08
Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same…: by…
C07C 41/26
By reactions not forming ether-oxygen bonds: by introduction of hydroxy or O-metal groups
C07C 43/23
Having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring: containing hydroxy or O-metal groups

Family

US 10,752,575 B2Related patent
US 2019/0161432 A1This patent

From the US filing history. Foreign family members aren’t listed.

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