US 2019/0160177 A1 · METHOD FOR INCREASING THE BIOAVAILABILITY OF INHALED COMPOUNDS

Abstract

The present invention relates to a compound comprising one or more PEG moieties, wherein said compound is a therapeutic agent active for treating a respiratory disease. The present invention also relates to a method for preventing and/or treating a respiratory disease in a subject in need thereof comprising the administration of a PEGylated therapeutic agent. Another object of the invention is a method for enhancing the bioavailability of a therapeutic agent, for enhancing the pulmonary residency of a therapeutic agent and/or for reducing the pulmonary clearance of a therapeutic agent, wherein said methods comprise the PEGylation of the therapeutic agent.

Claims18

Dependent claims

A method of preventing and/or treating a respiratory disease in a subject in need thereof comprising the administration to the said subject of an effective amount of a PEGylated therapeutic agent.

Dependencies are inferred from the claim text.

Facts

Application

16/263,401Filed 31 Jan 2019

Priority

EP 14151665.817 Jan 2014

Published

30 May 2019

Term ends

Not estimatedThe source records don’t support an estimate.

Classification19 codes

A61K 47/60
Obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes: the organic…
A61K 9/0043
Galenical forms characterised by the site of application: nose
A61K 9/007
Galenical forms characterised by the site of application: pulmonary tract; Aromatherapy
A61K 38/47
Hydrolases: acting on glycosyl compounds , e.g. cellulases, lactases

Method for increasing the bioavailability of inhaled compounds

Life of this patent

Method for increasing the bioavailability of inhaled compounds

Life of this patent

Abstract

Claims18