Methods and agents to treat tumor cells and cancer
AssigneeTianxin Wang
InventorTianxin Wang
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Abstract
This disclosure provides cell surface anchoring conjugates, formulations comprising cell surface anchoring conjugates, TLR agonist and methods of using the same for boosting immunity in a subject and treating tumor cell and cancer.
Claims16
A cell surface anchoring conjugate comprising at least one antigen covalently bonded to a lipid moiety, or an analogue or derivative thereof, optionally via linker, wherein the antigen is a mimotope of a recombinant antibody.
A pharmaceutical composition comprising a cell surface anchoring conjugate and a Toll-like receptors (TLR) agonist, wherein the cell surface anchoring conjugate comprises a mimotope antigen of a recombinant antibody.
A method of treating and/or inhibiting a tumor cell, comprising administering to a patient in need thereof a therapeutically effective amount of a mixture of the cell surface anchoring mimotope antigen conjugate and a Toll-like receptors (TLR) agonist together with a recombinant antibody that can binds with the antigen.
Dependencies are inferred from the claim text.