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US 2019/0160126 A1Published application
Compositions and methods for treating reproductive indicators symptomatic of male infertility
OwnerOmar Saleh ALAFFARIinventor
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Abstract
A nutraceutical composition containing (i) garden cress, (ii) nigella saliva, (iii) commiphora myrrha, and (iv) fenugreek for treating male infertility and a method of treating symptomatic reproductive indicators of male infertility such as sperm concentration, sperm count, and progressive sperm motility by administering an effective amount of the nutraceutical composition having an effective proportion of each constituent.
Claims20
1:
- A nutraceutical composition for treating male infertility, the composition comprising:
- (i) garden cress;
- (ii) nigella sativa;
- (iii) commiphora myrrha;
- and
- (iv) fenugreek;
- wherein each constituent (i), (ii), (iii) and (iv) is present in an effective amount and an effective proportion relative to the total amount of (i)-(iv) such that when administered to a male human subject in need thereof the nutraceutical composition is effective in increasing at least one reproductive indicator selected from the group consisting of sperm concentration, sperm count, and progressive sperm motility relative to the reproductive indicator prior to the administering.
4 more elements
2:
- The nutraceutical composition of claim 1, further comprising (v) a pharmaceutically acceptable carrier or excipient.
3:
- The nutraceutical composition of claim 1, which has a wet basis moisture content of less than 15% relative to the total weight of the nutraceutical composition.
4:
- The nutraceutical composition of claim 1, which is in a powder form and has an average particle size of 0.1-2.5 mm.
5:
- The nutraceutical composition of claim 1, wherein a weight ratio of garden cress to nigella sativa to commiphora myrrha to fenugreek is in the range of 5-10:5-10:0.25-2.0:2-6.
6:
- The nutraceutical composition of claim 1, wherein a weight ratio of garden cress to nigella sativa to commiphora myrrha to fenugreek is 7:7:1:4.5.
7:
- A method of increasing at least one reproductive indicator selected from the group consisting of sperm concentration, sperm count, and progressive sperm motility, the method comprising:
- administering to a male human subject in need thereof an effective dosage of a nutraceutical composition to increase at least one reproductive indicator selected from the group consisting of sperm concentration, sperm count, and progressive sperm motility, the nutraceutical composition comprising:
- (i) garden cress;
- (ii) nigella sativa;
- (iii) commiphora myrrha;
- and
- (iv) fenugreek;
- wherein each constituent (i), (ii), (iii) and (iv) is present in an effective amount and an effective proportion relative to the total amount of (i)-(iv) stich that when administered to the male human subject the nutraceutical composition is effective in increasing at least one reproductive indicator selected from the group consisting of sperm concentration, sperm count, and progressive sperm motility relative to the reproductive indicator prior to the administering.
5 more elements
8:
- The method of claim 7, wherein the nutraceutical composition further comprises (v) a pharmaceutically acceptable carrier or excipient.
9:
- The method of claim 7, wherein the nutraceutical composition has a weight ratio of garden cress to nigella sativa to commiphora myrrha to fenugreek in the range of 5-10:5-10:0.25-2.0:2-6.
10:
- The method of claim 7, wherein the nutraceutical composition has a weight ratio of garden cress to nigella sativa to commiphora myrrha to fenugreek of 7:7:1:4.5.
11:
- The method of claim 7, wherein the administering is performed in an enteral manner.
12:
- The method of claim 7, wherein the nutraceutical composition is administered in the form of an encapsulated powder.
13:
- The method of claim 7, wherein the nutraceutical composition is administered at a dosage in the range of 1-10 mg at least once per day.
14:
- The method of claim 7, wherein the administering is performed 1-5 times daily.
15:
- The method of claim 7, wherein the administering is performed 1-5 times daily for a time period of 5-150 days.
16:
- The method of claim 7, which increases at least one reproductive indicator in the male human subject selected from the group consisting of sperm concentration, sperm count, and progressive sperm motility by 40-80% relative to the at least one reproductive indicator in the male human subject selected from the group consisting of sperm concentration, sperm count, and progressive sperm motility prior to the administering.
17:
- A nutraceutical beverage for treating male infertility, the beverage comprising:
- (i) garden cress;
- (ii) nigella sativa:
- (iii) commiphora myrrha;
- (iv) fenugreek;
- and
- (vi) a liquid;
- wherein each constituent (i), (ii), (iii) and (iv) is present in an effective amount and an effective proportion relative to the total amount of (i)-(iv) such that when administered to a male human subject in need thereof the nutraceutical beverage is effective in increasing at least one reproductive indicator selected from the group consisting of sperm concentration, sperm count, and progressive sperm motility relative to the reproductive indicator prior to the administering.
5 more elements
18:
- The nutraceutical beverage of claim 17, wherein a weight ratio of garden cress to nigella sativa to commiphora myrrha to fenugreek is in the range of 5-10.0:5-10:0.25-2.0-2.6.
19:
- The nutraceutical beverage of claim 17, wherein a weight ratio of garden cress to nigella sativa to commiphora myrrha to fenugreek is 7:7:1:4.5.
20:
- The nutraceutical beverage of claim 17, wherein a ratio of total weight of (i)-(iv) in grams to total volume of the nutraceutical beverage is in the range of 1:5 to 1:100.