Probiotic Formulations for Improving Athletic Performance

A method of altering bacterial species within a human comprising increasing population of one or more bacterial strains selected from the group consisting of genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, and phylum cyanobacteria.

A method of supplementing bacterial species within a human before, during, or after physical activity comprising increasing population of one or more bacterial species selected from the group consisting of genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, and phylum cyanobacteria.

A method of increasing or maintaining training endurance or performance endurance of a human comprising increasing population of one or more bacterial species selected from the group consisting of genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, and phylum cyanobacteria.

A method of reducing lactate levels in a human during or after physical activity generating increased lactate levels comprising increasing within the human one or more bacterial species selected from the group consisting of genus Veillonella, genus Oscillospira, and genus Ruminococcus.

A method of reducing inflammation within a human resulting from physical activity comprising increasing within the human one or more bacterial species selected from the group consisting of genus Faecalibacterium, genus Phascolarctobacteria, genus Bacteroides, genus Blautia and genus Dialister.

A method of increasing energy metabolism within a human during physical activity comprising administering to the human phylum cyanobacteria.

A method of improving or maintaining athletic training, performance or recovery by a human during physical activity comprising increasing population of one or more bacterial species selected from the group consisting of genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, and phylum cyanobacteria.

A method of recovering from physical activity resulting in inflammation and increased lactate levels comprising increasing a population of one or more bacterial species selected from the group consisting of genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, and phylum cyanobacteria within a human.

A method of promoting weight loss or fitness by a human comprising increasing a population of bacteria from the family Christensenellaceae within the human.

An animal model including one or more bacterial species selected from the group consisting of genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, and phylum cyanobacteria which represent the microbiome of an athlete.

A method of screening a compound that modulates the microbiome of an athlete comprising administering a test compound to an animal including one or more bacterial species selected from the group consisting of genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, and phylum cyanobacteria, and determining the level of the one or more bacterial species selected from the group consisting of genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, and phylum cyanobacteria.

A method of supplementing the microbiome of an athlete after exercise comprising administering one or more bacterial species that improve activity of the xenobiotic metabolism pathway of the athlete.

A method of supplementing the microbiome of an athlete after exercise comprising administering one or more bacterial species that improve the starch and sucrose metabolism pathway of the athlete.

A method of determining bacterial species either uniquely associated with, altered in abundance within, or altered in activity within a first individual with a regular exercise regimen compared to a control individual without a regular exercise regimen comprising

• sequencing a first fecal sample from the first individual to identity the bacterial species present and active in the first fecal sample,
• sequencing a control fecal sample from the control individual to identity the bacterial species present and active in the control fecal sample, and
• comparing the bacterial species present and active in the first fecal sample to the bacterial species present and active in the control fecal sample to identify bacterial species increased or decreased in the first fecal sample compared to the control fecal sample.

A method of enriching and/or isolating a lactic acid fermenting bacteria comprising

• contacting a biological sample to a substrate including lactate,
• incubating the biological sample for a period of time and at a temperature sufficient for growth of lactic acid consuming bacteria.