Use of a bisphosphonate salt in a medicament for a naturally occurring disease/disorder in a mammal

A medicament compound comprising a salt of a nitrogen containing bisphosphonic acid (bisphosphonate) according to FIG. 1a

• wherein R1 is independently selected from H and OH,
• wherein R2 is independently selected from branched, unbranched, aromatic, non-aromatic cyclic, carbon comprising moieties having 1-12 carbon atoms and at least one of a primary amine, secondary amine, tertiary amine, or heterocycle comprising nitrogen, an analogue of said bisphosphonate, and combinations thereof,
• for treating a naturally occurring disease/disorder in a mammal, comprising only the bisphosphonate or analogue thereof as active compound, wherein the disease/disorder is one or more of degenerative arthritis, degenerative joint disease, osteoarthrosis, arthritis, and Osteoarthritis, the mammal being selected from the orders of Perissodactyla, (Cet) Artiodactyla, and Carnivora,
• wherein the medicament is a physiological liquid comprising a dosage of 0.01-1 mg/kg bisphosphonate,
• wherein the medicament is for application once per 1-12 months, and
• wherein the medicament is for sub-cutaneous or intravenous or intraperiotenal provision.