Small molecule inhibition for preventing or treating fibrotic diseases
AssigneeThe Regents of the University of California
InventorsGino Cortopassi, Alexey Tomilov, Natalie Torok, XiaoSong Jiang
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Abstract
The present invention provides methods for preventing or treating a fibrotic disease in a subject. In some embodiments, the fibrotic disease is fatty liver disease, non-alcoholic fatty liver disease, or non-alcoholic steatohepatitis. In particular aspects, the methods comprise administering a small molecule inhibitor of Shc to achieve pharmacological suppression of Shc protein activity in the subject.
Claims15
A method for preventing or treating a fibrotic disease in a subject, the method comprising administering to the subject an effective amount of a small molecule inhibitor of Shc to achieve pharmacological suppression of Shc protein activity in the subject.
Dependencies are inferred from the claim text.