Oral delivery system comprising two compartments

A method for oral delivery comprising:

• disposing in a first delivery compartment a first component comprising natural unbranched polysaccharide, the first delivery compartment having a first delivery opening;
• disposing in a second delivery compartment containing a second component comprising multivalent cations, the second delivery compartment having a second delivery opening;
• providing an actuator for controlling the delivery of the first and second components from the respective first and second compartments to the first and second delivery openings;
• and
• controlling the actuator to deliver the first and second components to a target oral mucosal area in an oral cavity so that the first and second components are delivered in a synchronized manner to the target oral mucosal area in the oral cavity to form a bioadhesive gel from the natural unbranched polysaccharide and the multivalent cations in a cross-linking reaction proximate to the target oral mucosal area.

A method for oral delivery comprising:

• delivering from a first delivery compartment a first component comprising natural unbranched polysaccharide to a target oral mucosal area in an oral cavity;
• delivering from a second delivery compartment a second component comprising multivalent cations to the target oral mucosal area in the oral cavity;
• and
• synchronizing the delivery of the first and second components to the target oral mucosal area so that the first and second components are delivered in a synchronized manner to the target oral mucosal area in the oral cavity to form a bioadhesive gel from the natural unbranched polysaccharide and the multivalent cations in a cross-linking reaction proximate to the target oral mucosal area.

A method for oral delivery comprising:

• providing a first compartment having a first compartment output and a second compartment having a second compartment output, the first compartment containing a first component comprising natural unbranched polysaccharide, the second compartment containing a second component comprising multivalent cations,
• interfacing, with first fluid conduit, an interior of the first compartment to a first fluid conduit delivery opening;
• interfacing, with a second fluid conduit, an interior of the second compartment to a second fluid conduit delivery opening;
• providing an actuator for controlling the delivery of the first and second components from the respective first and second compartments to a target oral mucosal area in an oral cavity via the respective first and second fluid conduit delivery openings;
• and
• controlling the actuator to deliver the first and second components so that the first and second components are administered in a synchronized manner to the target mucosal area in the oral cavity to form a bioadhesive gel from the natural unbranched polysaccharide and the multivalent cations in a cross-linking reaction proximate to the target oral mucosal area.