Composition for solid preparation, solid preparation, and method for producing the same

A method for producing a tablet, the method comprising steps of:

• dry-mixing hydroxypropyl methyl cellulose having a polydispersity of 4.0 or more, as determined by absolute molecular weight measurement, and a viscosity at 20° C. of 1,500 to 150,000 mPa·s, as determined in a 2% by mass aqueous solution, with an active ingredient to obtain a mixture;
• and
• tableting the mixture to obtain a tablet.

A method for producing a tablet, the method comprising steps of:

• granulating a mixture comprising hydroxypropyl methyl cellulose having a polydispersity of 4.0 or more, as determined by absolute molecular weight measurement, and a viscosity at 20° C. of 1,500 to 150,000 mPa·s, as determined in a 2% by mass aqueous solution, and an active ingredient to obtain a granulated product;
• and
• tableting the granulated product to obtain a tablet.

A method for producing hydroxypropyl methyl cellulose, comprising steps of:

• bringing low-polymerization-degree pulp having an intrinsic viscosity of 300 to 700 ml/g and high-polymerization-degree pulp having an intrinsic viscosity of 750 to 2,500 ml/g into contact with an alkali metal hydroxide solution to obtain alkali cellulose;
• and
• reacting the alkali cellulose with an etherifying agent to obtain hydroxypropyl methyl cellulose having a polydispersity of 4.0 or more, as determined by absolute molecular weight measurement, and having a viscosity at 20° C. of 1,500 to 150,000 mPa·s, as determined in a 2% by mass aqueous solution.