Point-of-care tele monitoring device for neurological disorders and neurovascular diseases and system and method thereof

A bi-directional, decision-tree based Point of Care (POC) system, the system comprising:

• Point of Care (POC) device(s) that comprising one or more sensors capable to acquire multiple bio-signals from brain and/or body within a body area network;
• a Detection module configured to receive signal for either the whole brain or a region of interest as well as corresponding sensor location information and perform analysis;
• an Electronics/electrical component(s) of the device configured to capture one or more bio-signals from the sensors as distinct but synchronized signals;
• a Storage for locally storing data relating to the sensors such that the sensors are reconfigured to focus on a region of interest for the Detection module;
• a Processing module for comparing the detected abnormalities in the analysis values with a reference signal values;
• a Display module for displaying a content based in part on the data output from said Detection module, wherein the content comprises a signal indicative of the presence or absence and/or severity of the neuro-glial-vascular dysfunction;
• a Transfer module to bidirectionally transfer the data wirelessly to a remote monitoring center and for synchronizing streaming data for live analysis or recording
• an internet of things enabled component with a Graphical User Interface (GUI) of the device interacting with the electronics/electrical component wirelessly or in a wired manner to receive the bio-signals as well as captures patient's vitals and other pertinent medical information from multiple sources and transfers the bio-signals along with the patient's medical information to a tele-monitoring platform;
• and
• a multi-level, decision-tree based diagnosis and triaging deployed in the telemonitoring platform analyzes the “input”, aggregates the output decision at each level of the decision tree and provides the output decision as input to next level of the decision-tree system leading towards accurate diagnosis of patient's medical condition.

A Point of Care (POC) system for determining neuro-glial-vascular interaction, wherein the system comprising:

• one or more sensor (re)configured to sense a particular characteristic indicative of a neurological or psychiatric condition or state;
• means for receiving an input from one or more remotely configurable sensors to target a cortical region of interest, and developing treatment parameters based on the input data;
• a determination means configured to receive NIRS and EEG signal and perform analysis remotely;
• means for storing and comparing the data relating to NIRS and EEG signal generated by the determination means for comparing the detected abnormalities in NIRS and EEG values with a reference signal values;
• means for the human and/or software agents to remotely query a specific neural tissue or cortical location (region of interest) from the whole-head distribution of EEG and NIRS sensors at the point of care (POC);
• means of finding the subject specific shape of the cap, e.g., based on the impedance changes in the cap material, and therefore the EEG and NIRS sensor locations such that the sensor montage can automatically re-configured from the whole-head distribution at the POC device based on pre-computed sensitivity function of the sensor locations;
• a display means for displaying a content based in part on the data output from said determination means, wherein the content comprises a signal indicative of the presence or absence and/or severity and a transfer means to transfer the data wirelessly to a remote monitoring center to take the required decision with the Diagnosis module,
• wherein the system characterized in that utilizes two or more sensor modalities such as multi-wavelength optical and electrophysiological, which are used simultaneously to target same neural substrate in a single sensor montage using beam-forming approaches to enables effective point of care monitoring of the neurological disorders and neurovascular diseases.

A point-of-care monitoring (POCT) method for neuro-glial-vascular interactions, wherein the method comprising:

• receiving an input of a neurological or psychiatric condition from one or more sensors and developing treatment parameters based on the input data,
• determining the signals received from electroencephalography (EEG) is used with Near Infrared spectroscopy (NIRS) and comparing the data relating to NIRS and EEG signal for the detected abnormalities values with a reference signal values,
• further analyzing and transferring the data wirelessly to a remote monitoring center to take the required decision,
• wherein the method characterized in that utilizes two or more sensor modalities such as multi-wavelength optical and electrophysiological, which are used simultaneously to target same neural substrate in a single sensor montage using beam-forming approaches to enables effective point of care monitoring of the neurological disorders and neurovascular diseases.