Silicone Hydrogel Contact Lenses Having Improved Lubricity
AssigneeCooperVision International Holding Company, LP
InventorsVictoria Rogers, Melanie George, Andrew Luk
Life of this patent
Estimating the term…
Abstract
Silicone hydrogel contact lenses are packaged in a packaging solution including an ophthalmically-acceptable concentration of a surfactant to provide a contact lens having a lower coefficient of friction compared to a control lens that is not packaged in the surfactant. The surfactant is a poly(ethylene oxide) (PEO)-containing surfactant having a molecular weight of up to about 6,000 daltons, or is an alkyl aryl-containing surfactant, or is both an alkyl aryl and PEO-containing surfactant having a molecular weight of up to about 6,000 daltons. Methods of manufacturing silicone hydrogel contact lenses are also described.
Claims42
1-41. (canceled)
An unworn sterile silicone hydrogel contact lens immersed in a packaging solution and sealed in a package, wherein the packaging solution comprises an ophthalmically-acceptable concentration of from 0.01 wt. % up to 0.5 wt. % of an alkyl aryl-containing surfactant, wherein the contact lens has a lower coefficient of friction after an overnight wash compared to a control lens that has not been contacted with the alkyl aryl-containing surfactant but is otherwise identical.
An unworn sterile silicone hydrogel contact lens immersed in a packaging solution and sealed in a package, wherein the packaging solution comprises from 0.01 wt. % to 0.1 wt. % tyloxapol, and wherein the contact lens has a lower coefficient of friction after an overnight wash compared to a control lens that has not been contacted with the tyloxapol but is otherwise identical.
A contact lens package comprising:
- a base member having a cavity for accommodating a packaging solution and a contact lens;
- an unworn silicone hydrogel contact lens in the cavity of the base member;
- and
- a packaging solution in the cavity of the base member, wherein the packaging solution comprises from 0.01 wt. % to 0.1 wt. % tyloxapol.
An unworn sterile silicone hydrogel contact lens immersed in a packaging solution and sealed in a package, wherein the packaging solution comprises an ophthalmically-acceptable concentration of from 0.01 wt. % up to 0.5 wt. % of a poly(ethylene oxide) (PEO)-containing surfactant having an absolute number average molecular weight of up to 6,000 daltons, wherein the contact lens has a lower coefficient of friction after an overnight wash compared to a control lens that has not been contacted with the PEO-containing surfactant but is otherwise identical.
A method of manufacturing an ophthalmically-acceptable silicone hydrogel contact lens comprising:
- a) curing a polymerizable composition comprising at least one silicone monomer and at least one hydrophilic monomer to form a polymeric lens body;
- b) packaging the polymeric lens body with a packaging solution comprising an alkyl aryl-containing surfactant, wherein the packaging solution has a concentration of the alkyl aryl-containing surfactant of from 0.01 wt. % up to 0.5 wt. % prior to contact with polymeric lens body;
- and
- c) heating the packaged polymeric lens body to provide an unworn, sterilely packaged contact lens,
- wherein the contact lens has a lower coefficient of friction after an overnight wash compared to a control lens that has not been contacted with the alkyl aryl-containing surfactant but is otherwise identical.
A method of manufacturing an ophthalmically-acceptable silicone hydrogel contact lens comprising:
- a) curing a polymerizable composition comprising at least one silicone monomer and at least one hydrophilic monomer to form a polymeric lens body;
- b) packaging the polymeric lens body with a packaging solution comprising a poly(ethylene oxide) (PEO)-containing surfactant having an absolute number average molecular weight of up to 6,000 daltons, wherein the packaging solution has a concentration of the PEO-containing surfactant of from 0.01 wt. % up to 0.5 wt. % prior to contact with polymeric lens body;
- and
- c) heating the packaged polymeric lens body to provide an unworn, sterilely packaged contact lens,
- wherein the contact lens has a lower coefficient of friction after an overnight wash compared to a control lens that has not been contacted with the PEO-containing surfactant but is otherwise identical.
Dependencies are inferred from the claim text.