Compositions and methods for screening, monitoring and treating gastrointestinal diseases
AssigneeBioCrypton Inc.
InventorsValeria S. Ossovskaya, Olga Potapova, Ilya Mazo
Life of this patent
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Abstract
Provided are compositions and methods for screening, monitoring and treating a gastrointestinal (GI) cancer patient. In the methods, the patient's sample is screened for a profile of abnormal pathways and glycosylated protein biomarkers indicative of a GI cancer.
Claims21
A method for screening, monitoring and/or treating a gastrointestinal (GI) cancer patient, the method comprising:
- obtaining a sample from the patient,
- isolating glycosylated proteins from the sample,
- analyzing the isolated glycosylated proteins for biomarkers listed in Tables 1A, 2A, 3A, 4A, 5A, 6A, 7A, or any combination thereof, and/or
- grouping the isolated glycosylated proteins into a profile of pathways, and
- matching the obtained profile at least partially with at least one profile selected from the group of profiles of Tables 1, 2, 3, 4, 5, 6, 7, 8, and any combination thereof.
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A method for detecting or monitoring a disorder of the pancreas, the method comprising obtaining a sample from a patient and testing the sample for at least one or more biomarker and/or glycobiomarker selected from Tables 5A, 5, 6A, 6 and 9.
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A method for treating a disorder of the pancreas, the method comprising obtaining a sample from a mammal in need of the treatment and testing the sample for at least one or more biomarker and/or glycobiomarker selected from Tables 5A, 5, 6A, 6 and 9.
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Dependencies are inferred from the claim text.