Analysis of measurements of a polymer
AssigneeOxford Nanopore Technologies PLC
InventorsStuart William Reid, James Anthony Clarke, James White, Gavin Harper
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Abstract
A time-ordered series of measurements of a polymer made during translocation of the polymer through a Nanopore are analysed. The measurements are dependent on the identity of k-mers in the Nanopore, a k-mer bring k polymer units of the polymer, where k is a positive integer. The method involves deriving, from the series of measurements, a feature vector of time-ordered features representing characteristics of the measurements; and determining similarity between the derived feature vector and at least one other feature vector.
Claims28
A method of analyzing a time-ordered series of measurements of a polymer made during translocation of the polymer through a nanopore, wherein the measurements are dependent on the identity of k-mers in the nanopore, a k-mer being k polymer units of the polymer, where k is a positive integer, the method comprising:
- deriving, from the series of measurements, a feature vector of time-ordered features representing characteristics of the measurements;
- and
- determining similarity between the derived feature vector and at least one other feature vector.
17-21. (canceled)
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29-35. (canceled)
An analysis device configured to analyze a time-ordered series of measurements of a polymer made during translocation of the polymer through a nanopore, wherein the measurements are dependent on the identity of k-mers in the nanopore, a k-mer being k polymer units of the polymer, where k is a positive integer, the device comprising:
- means for deriving, from the series of measurements, a feature vector of time-ordered features representing characteristics of the measurements;
- and
- means for determining similarity between the derived feature vector and at least one other feature vector.
Dependencies are inferred from the claim text.