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AssigneeHenan University
InventorsWeidong CHEN, Xiaobo NIE, Yandong WANG, Yun ZHOU, Xinrui LV
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MicroRNA, including one of or a combination of the following components: (a) a pri-miRNA of miR-149-3p; (b) a pre-miRNA of miR-149-3p; (c) a mature miRNA of miR-149-3p; (d) a miR-149-3p derivative; (e) a 18-26 nucleotides miRNA having a sequence of 5′-AGGGAGG-3′; and (f) a derivative of the 18-26 nucleotides miRNA of (e). Also provided is a method for treating a metabolic disease. The method includes employing a DNA sequence encoding miR-149-3p as a target gene, constructing an overexpression vector of the miR-149-3p, preparing a pharmaceutical composition including the overexpression vector of the miR-149-3p, and administering the pharmaceutical composition to a patient in need thereof.
MicroRNA, comprising one of or a combination of the following:
A method for treating a metabolic disease, the method comprising employing a DNA sequence encoding miR-149-3p as a target gene, constructing an overexpression vector of the miR-149-3p, preparing a pharmaceutical composition comprising the overexpression vector of the miR-149-3p, and administering the pharmaceutical composition to a patient in need thereof.
Dependencies are inferred from the claim text.