US 2019/0153377 A1Published application

Sterile connector and cell culture device provided therewith

AssigneeHitachi High-Technologies Corporation

InventorsAkihiro SHIMASE, Eiichiro TAKADA, Kazumichi IMAI, Toshinari SAKURAI

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Abstract

A sterile connector has a first connector including a first housing provided with a first flow channel; a first pipeline connected to the first flow channel; first and second openings, the first opening being positioned inward from the second opening; and a first sealing member covering the second opening. Also, a second connector includes a second housing provided with a second flow channel; a third opening; and a second sealing member covering the third opening. The first and second connectors are detachable from each other. The first sealing member seals a space between the inner circumferential surface of the first housing and the outer circumferential surface of the second housing, while the second sealing member seals a space between the inner circumferential surface of the second housing and the outer circumferential surface of the first pipeline so that the first flow channel communicates with the second flow channel.

Claims19

Dependent claims

A sterile connector comprising:

a first connector that is provided with a first housing having a first flow channel for causing a fluid to flow therethrough, a first pipeline which is continuous to the first flow channel, a first opening to which one end of the first pipeline is opened, a second opening which is demarcated with an end portion of the first housing, and a first sealing member which covers the second opening with the first opening positioned inward from the second opening in an axial direction of the first housing;
and
a second connector that is provided with a second housing having a second flow channel for causing a fluid to flow therethrough, a third opening which is demarcated with an end portion of the second housing, and a second sealing member which covers the third opening,
wherein the first and second connectors are attachable to and detachable from each other,
wherein the first sealing member seals a gap between an outer circumferential surface of the second housing and an inner circumferential surface of the first housing with which the second opening is demarcated, and
wherein the second sealing member seals a gap between an outer circumferential surface of the first pipeline and an inner circumferential surface of the second housing with which the third opening is demarcated, and the first flow channel communicates with the second flow channel through the second sealing member.

3 more elements

A cell culture device comprising:

a cell culture vessel that is provided with an inflow channel through which a liquid for culture circulates and an outflow channel through which the liquid is discharged after use;
and
an integrated flow-channel member that is configured to connect a plurality of cell culture vessels in parallel, that is provided with an upstream-side divergence flow channel and a downstream-side divergence flow channel which correspond to the cell culture vessels, and that sends a liquid for culture to any desired cell culture vessel of the plurality of cell culture vessels, that is, to the inflow channel via the upstream-side divergence flow channel,
wherein the integrated flow-channel member is provided with a first housing having a first pipeline that is continuous to each of the upstream-side divergence flow channel and the downstream-side divergence flow channel, a first opening to which one end of the first pipeline is opened, a second opening which is demarcated with an end portion of the first housing, and a first sealing member which covers the second opening,
wherein the cell culture vessel is provided with a second housing having each of the inflow channel and the outflow channel, a third opening which is demarcated with an end portion of the second housing, and a second sealing member which covers the third opening, and
wherein the first sealing member seals a gap between an inner circumferential surface of the first housing and an outer circumferential surface of the second housing, the second sealing member seals a gap between the second housing and an outer circumferential surface of the first pipeline, and the cell culture vessel is connected to the integrated flow-channel member.

3 more elements

A cell culture device comprising:

a cell culture vessel that is provided with an inflow channel through which a liquid for culture circulates and an outflow channel through which the liquid is discharged after use;
and
an integrated flow-channel member that is configured to connect a plurality of cell culture vessels in parallel, that is provided with an upstream-side divergence flow channel and a downstream-side divergence flow channel which correspond to the cell culture vessels, and that sends a liquid for culture to any desired cell culture vessel of the plurality of cell culture vessels, that is, to the inflow channel via the upstream-side divergence flow channel,
wherein the cell culture vessel is provided with a first housing having a first pipeline that is continuous to each of the inflow channel and the outflow channel, a first opening to which one end of each of the first pipelines is opened, a second opening which is demarcated with an end portion of the first housing, and a first sealing member which covers the second opening,
wherein the integrated flow-channel member is provided with a second housing having each of the upstream-side divergence flow channel and the downstream-side divergence flow channel, a third opening which is demarcated with an end portion of the second housing, and a second sealing member which covers the third opening, and
wherein the first sealing member seals a gap between an inner circumferential surface of the first housing and an outer circumferential surface of the second housing, the second sealing member seals a gap between the second housing and an outer circumferential surface of the first pipeline, and the cell culture vessel is connected to the integrated flow-channel member.

3 more elements

Dependencies are inferred from the claim text.