Methods for the treatment of bladder cancer
AssigneeViralytics Limited
InventorsDARREN SHAFREN, Gough Au, Hardev Pandha, Guy Simpson
Life of this patent
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Abstract
The present invention relates to methods of treating bladder cancer with human enterovirus C (HEC) in combination with chemotherapy or radiation therapy. The present invention also relates to methods for increasing susceptibility of a cancer cell to infection by HEC.
Claims40
A method for the treatment of bladder cancer in a subject, the method comprising administering to said subject a therapeutically effective amount of a human enterovirus C (HEC) in combination with radiotherapy or chemotherapy.
A method of increasing susceptibility of a cancer cell to infection with an HEC virus, the method comprising exposing said cancer cell to a chemotherapeutic agent or to radiation before exposing said cell to the HEC virus.
A method for enhancing oncolytic treatment of a subject having bladder cancer, wherein the oncolytic treatment comprises administration of a HEC virus to said subject, the method comprising administering to said subject a chemotherapeutic agent prior to administering to said subject the HEC virus.
A method for enhancing oncolytic treatment of a subject having bladder cancer, wherein the oncolytic treatment comprises administration of a HEC virus to said subject, the method comprising administering to said subject one or more doses of radiation therapy prior to administering to said subject the HEC virus.
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Dependencies are inferred from the claim text.