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US 2019/0127726 A1Published application
Delivering enzyme using an injectable hydrogel depot
AssigneeSaint Louis University
InventorsAdriana M. Montaño, Silviya Petrova Zustiak, Era Jain
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Abstract
Compositions and methods for delivering enzymes in enzyme hydrogel formulations are disclosed. More particularly, the present disclosure relates to injectable enzyme hydrogel formulations and delivery of injectable enzyme hydrogel formulations. Also disclosed are methods for GALNS enzyme replacement therapy and lysosomal enzyme replacement therapy.
Claims20
A delivery system for delivering an enzyme hydrogel formulation comprising:
- an applicator and an enzyme hydrogel formulation, the enzyme hydrogel comprising an enzyme, a polymer, and a buffer solution.
A method for delivering an enzyme hydrogel formulation, the method comprising:
- preparing an injectable enzyme hydrogel formulation, the injectable enzyme hydrogel formulation comprising an enzyme, a polymer, and a buffer solution;
- introducing the enzyme hydrogel formulation into an applicator.
Dependencies are inferred from the claim text.