Non-beta lactam antibiotics

A compound of Formula (I):

• A-B-C-L-D (I)
• wherein
• A is pyrrolyl, pyrazolyl, imidazolyl, or indolyl, each optionally substituted with one to three RX groups;
• B is 1,2,4-oxadiazole, 1,3,4-oxadiazole, 1,2-oxazole, 1,3-oxazole, triazole, pyrazole, imidazole, or dihydro-imidazole;
• C is phenyl, bicyclic heteroaryl, or bicyclic heterocycle, wherein the phenyl or the bicyclic heteroaryl or heterocycle is optionally substituted with one or five RX groups;
• L is O, S, or NH;
• D is phenyl, heteroaryl, heterocycle, alkyl, aminoalkyl, hydroxyalkyl, or tert-butyloxycarbonyl, wherein the phenyl is optionally substituted with one to five RX groups;
• or -L-D is absent when C is bicyclic heteroaryl or heterocycle;
• each RX is independently —H, —OH, halo, —N3, —NO2, —O-allyl, —C≡N, —CF3, —OCF3, —C(═O)CF3, alkyl, alkoxy, phenyl, phenoxy, benzyl, or cycloalkyl —NRaRb, or —C≡C—RY;
• each Ra and Rb are independently H, alkyl, or a nitrogen protecting group;
• and
• RY is —H, alkyl, hydroxyalkyl, or a silicon protecting group;
• or pharmaceutically acceptable salt or solvate thereof.