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AssigneeGenomatica, Inc.
InventorsAnthony P. Burgard, Robin E. Osterhout, Stephen J. Van Dien, Cara Ann Tracewell, Priti Pharkya, Stefan Andrae
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Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 3-hydroxyisobutyrate or MAA. Also provided herein are methods for using such an organism to produce 3-hydroxyisobutyrate or MAA.
-71. (canceled)
A method of producing methyl ester of methacrylic acid (MMA), comprising culturing a non-naturally occurring microorganism in the presence of methanol under conditions and for a sufficient period of time to produce methacrylic acid (MAA), and esterifying the MAA with methanol to produce MMA.
Dependencies are inferred from the claim text.